Multiple treatment comparison of seven new drugs for patients with advanced malignant melanoma: a systematic review and health economic decision model in a Norwegian setting.

Objective: To assess the relative effectiveness and cost-effectiveness of seven new drugs (cobimetinib, dabrafenib, ipilimumab, nivolumab, pembrolizumab, trametinib and vemurafenib) used for treatment of patients with advanced malignant melanoma in the Norwegian setting.

Design: A multiple technology assessment.

Patients: Patients with advanced malignant melanoma aged 18 or older.

More Use of Peritoneal Dialysis Gives Significant Savings: A Systematic Review and Health Economic Decision Model.

Background: Patients with end-stage renal disease (ESRD) are in need of renal replacement therapy as dialysis and/or transplantation. The prevalence of ESRD and, thus, the need for dialysis are constantly growing. The dialysis modalities are either peritoneal performed at home or hemodialysis (HD) performed in-center (hospital or satellite) or home.

Cancer risk with folic acid supplements: a systematic review and meta-analysis.

Objective To explore if there is an increased cancer risk associated with folic acid supplements given orally. Design Systematic review and meta-analysis of controlled studies of folic acid supplementation in humans reporting cancer incidence and/or cancer mortality. Studies on folic acid fortification of foods were not included.

The National Poison Center in Norway: user satisfaction and a health economic evaluation.

Objectives: The aim of the study was to find out how satisfied users are with the National Poison Center of Norway and to make a health economic evaluation of the service.

Method: The material consisted of telephone interviews with 310 users of the service from the general public and 665 completed questionnaires from doctors and nurses.

Results: Most respondents were satisfied with the information and had followed the advice.