Publications by authors named "Eva Perroux-David"
Sunscreens are mainly characterized by their sun-protection factor (SPF), which is measured according to the in vivo gold standard ISO 24444. Although the SPF concept is simple, SPF values are difficult to measure, due to the rather high variability caused by the complex interaction of light and skin. For half a century, there have been attempts to correlate the costly and ethically controversial in vivo procedure with a non-invasive (in vitro) method.
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- Brain tumors, particularly glioblastomas, are the leading cause of cancer-related deaths in individuals under 40, with a very low survival rate.
- Researchers conducted a human kinome siRNA screen to find new drug targets that could enhance the effectiveness of temozolomide (TMZ), the standard treatment for glioblastoma.
- They discovered that ERK5 plays a crucial role in helping glioblastoma cells survive TMZ treatment, and higher ERK5 levels in tumors are linked to more aggressive cancers and lower patient survival rates, suggesting that targeting ERK5 could improve treatment outcomes.