Publications by authors named "Eva Padrao"
Nintedanib, an intracellular inhibitor targeting multiple tyrosine kinases, has emerged as a standard treatment for various fibrotic lung diseases. Despite its efficacy, side effects such as nausea, diarrhea, and hepatotoxicity often lead to dose reduction or discontinuation. In this retrospective analysis at an university hospital's interstitial lung disease clinic, we aimed to identify baseline characteristics associated with dose adjustment or treatment discontinuation.
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- Lung cancer frequently leads to serious oncologic emergencies, with a study of 82 patients revealing that brain metastasis was the most common type reported.
- The majority of patients were in stage IV, and combined with prominent adenocarcinoma histology, this led to a high 6-month mortality rate of 75.6%.
- Factors such as age, type of cancer, and treatment significantly influenced the timing of these emergencies, but access to healthcare during the COVID-19 pandemic did not show notable differences.
Background: Diffuse lung diseases (DLD) are characterized by different immunophenotypes in the bronchoalveolar lavage fluid (BALF). We aimed to evaluate the diagnostic value of BALF NK and NKT cell counts of patients with DLD and lymphocytic alveolitis.
Methods: We assessed 202 patients with DLD, who underwent BALF immunophenotyping.
Background: Accurate diagnosis is essential for successful management of diffuse lung disease (DLD). Histopathology may sometimes be necessary. Surgical lung biopsy, the gold standard, carries a risk of morbidity and mortality.
View Article and Find Full Text PDFInflammatory myofibroblastic tumor is a rare benign tumor that affects most commonly children and young adults. In the lung, it comprises less than 1% of all neoplasms. The authors describe the clinical, radiological, and pathologic features of 2 cases of incidentally discovered pulmonary inflammatory myofibroblastic tumors.
View Article and Find Full Text PDFIntroduction: Acute fibrinous and organizing pneumonia (AFOP) is a rare diffuse pulmonary disease, but it is not yet known whether it is a distinct form of interstitial pneumonia or simply a reflection of a tissue sampling issue.
Methods: Cross-sectional evaluation of clinical and radiological findings, treatments, and outcomes for patients with histologically confirmed AFOP at a tertiary university hospital between 2002 and 2015.
Results: Thirteen patients (7 women, 53.