Publications by authors named "Eva Karner"
Article Synopsis
- Preeclampsia (PE) is linked to reduced blood flow to the placenta, which can cause heart function changes in pregnant women; this study investigates these cardiac characteristics and their relationship with NT-proBNP levels.
- A retrospective analysis of 65 PE-diagnosed pregnant women was conducted using echocardiography, revealing normal left ventricular size and function, but impaired longitudinal contractility and borderline left atrial size.
- Increased NT-proBNP levels were associated with lower gestational age at delivery and were indicative of maternal cardiac changes, with a high preterm birth rate due to worsening PE or fetal health issues linked to placental insufficiency.
Background: Biorefineries usually focus on the production of low-value commodities, such as bioethanol, platform chemicals or single cell protein. Shifting production to bioactive compounds, such as antimicrobial peptides, could provide an opportunity to increase the economic viability of biorefineries.
Results: Recombinant production of the antimicrobial peptide pediocin PA-1 in Corynebacterium glutamicum was transferred from yeast extract-based media to minimal media based on lignocellulosic spent sulfite liquor.
This case report presents a patient with a monochorionic twin pregnancy, development of twin-twin transfusion-syndrome (TTTS) and polymicrogyria (PMG) of one fetus. Due to TTTS grade 3, fetoscopic laser ablation was performed at gestational week 16+1. Sonographic follow-up showed a cortical malformation of the right parietal lobe in the former donor, which was identified as PMG by MRI scans.
View Article and Find Full Text PDF(1) Background: Lower birth weight among newborns in higher altitudes has been well documented in previous literature. Several possible causes for this phenomenon have been investigated, including biophysiological adaptation, epigenetic or genetic mechanisms or lifestyle changes. This is the first study to show the effect modification of altitude and parity on the birth weight length ratio (BWLR) in women resident in moderate altitudes compared to a low sea level.
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- Fetal growth restriction (FGR) is linked to higher risks of stillbirth and developmental issues, making early prediction important for better treatment options and outcomes.
- A study analyzed 1,930 singleton pregnancies with low estimated fetal weight and found that lower levels of pregnancy-associated plasma protein A (PAPP-A) and higher uterine artery Doppler pulsatility index are associated with FGR.
- The results suggest that monitoring PAPP-A and pulsatility index in the first trimester can help predict cases of FGR, potentially leading to improved care for affected pregnancies.
Fetal dysrhythmias are common abnormalities, which can be categorized into three types: rhythm irregularities, tachyarrhythmias, and bradyarrhythmias. Fetal arrhythmias, especially in high-risk pregnancies, require special monitoring and treatment. The aim of this study was to assess the stillbirth and early and late neonatal mortality rates for pregnancies complicated by fetal dysrhythmias from one single tertiary referral center from 2000 to 2022.
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- The study focused on the rates of stillbirth and neonatal mortality in pregnancies with congenital heart disease (CHD) and chromosomal trisomies (13, 18, and 21) from 2000-2020.
- A total of 160 patients were evaluated, with 61.3% of families choosing to terminate the pregnancy; of those who continued, 25.8% experienced fetal death during pregnancy or delivery.
- Live birth rates varied significantly by trisomy: 47.6% for trisomy 13/18 and 87.8% for trisomy 21, with a substantial portion of trisomy 21 infants surviving their first year.