Publications by authors named "Eva Hertervig"
Article Synopsis
- A study compared remote magnetic navigation (RMN) and manual catheter navigation for atrial fibrillation (AF) ablation, involving 112 patients in the RMN group and 102 in the Manual group.
- Results showed that RMN significantly reduced fluoroscopy time and achieved better AF-free rates over time, while using more radiofrequency energy; total procedure time remained similar between the two methods.
- The study concludes that the latest RMN technique provides improved procedural and clinical outcomes for AF ablation compared to the manual technique, contradicting earlier findings.
Article Synopsis
- The study aimed to assess the effectiveness of the max electrogram-guided approach for treating cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) compared to the conventional linear radio-frequency (RF) ablation method.
- Results from 80 patients showed that the max electrogram-guided method required significantly less time and fewer RF applications to achieve sustained bi-directional CTI block, indicating its efficiency.
- The findings suggest that the max electrogram-guided approach is a better option for AFL ablation and may be recommended for regular clinical practice over the traditional linear method.
Article Synopsis
- The study aimed to establish reference values for the dispersion of repolarization in the right atrium of healthy pigs and to assess if regional mapping could estimate global dispersion.
- Monophasic action potentials were recorded from multiple sites in the right atrium of 10 pigs using the CARTO mapping system.
- Findings revealed that global dispersion metrics were significantly greater than those from regional areas, indicating that regional mapping is not sufficient for evaluating overall atrial repolarization dispersions.
Article Synopsis
- The study investigates pulmonary vein (PV) potentials in patients with atrial fibrillation (AF) compared to those without AF, specifically patients with concealed Wolff-Parkinson-White (WPW) syndrome.
- Results showed that typical PV potentials were found in 91% of PVs in AF patients, while only 11% of PVs showed these potentials in WPW patients; moreover, AF patients had significantly longer conduction times.
- The findings suggest that the presence of complex PV potentials and prolonged conduction time are closely linked to AF, highlighting a difference between AF and non-AF patients regarding PV activity.
Article Synopsis
- The study aimed to analyze the total dispersion of ventricular repolarization in the epi- and endocardium by recording monophasic action potentials (MAP) from various sites in the hearts of pigs during controlled pacing.
- Results indicated that the total dispersions of activation time, end of repolarization time, and MAP duration were significantly larger than those measured in individual layers, highlighting a notable difference in repolarization between the epi- and endocardium.
- The findings demonstrate that the mapping technique used for epicardial repolarization is effective, and both layers of the heart contribute significantly to overall repolarization dispersion.
Article Synopsis
- The study aimed to examine the speeds of blood flow in the coronary sinus and the area of conduction delay between the atria in patients with paroxysmal atrial fibrillation (AF) compared to those without AF.
- Researchers analyzed 13 patients with paroxysmal AF and 10 control patients using a high-tech mapping system to measure activation times and velocities in specific heart areas.
- Results showed that AF patients had significantly slower blood flow velocities across the coronary sinus ostium compared to controls, highlighting a connection between slower interatrial conduction and the presence of paroxysmal AF.
Article Synopsis
- Activation recovery time (ART) is investigated as a potential measure of myocardial repolarization compared to end-of-repolarization (EOR) times from monophasic action potentials (MAP).
- A study involving 12 patients recorded ART and EOR simultaneously, revealing a strong correlation between the two measurements across various ventricular sites.
- The findings suggest that ART can effectively estimate global ventricular repolarization sequences and dispersion, making it a valuable tool in cardiac assessments.
Article Synopsis
- A study evaluated local ventricular refractoriness and its dispersion during induced ventricular fibrillation (VF) in 11 patients with an implantable cardioverter defibrillator (ICD) using a non-invasive method.
- Electrograms from the right ventricular (RV) apex and the lower esophagus showed significant differences in local ventricular activities during VF, with shorter estimated ventricular effective refractory periods (VERPs) compared to those measured during sinus rhythm.
- The findings indicated a maximal dispersion of estimated VERPs during VF that was notably greater than previous reports, confirming the effectiveness of this approach for assessing refractoriness in patients with ICDs.
Concealed conduction and dual pathway physiology of the atrioventricular node.
J Cardiovasc Electrophysiol
February 2004
Article Synopsis
- The study investigates the relationship between concealed conduction and dual pathway physiology in the AV node, particularly how these factors play a role in AV nodal reentrant tachycardia, a common heart rhythm disorder.
- Researchers conducted experiments on 20 patients with AV nodal reentry and 14 control patients, analyzing AV conduction curves before and after a procedure known as slow pathway ablation.
- Findings show that while most patients exhibited duality in AV conduction without any blocked impulses, this duality significantly decreased in the presence of a blocked impulse; additionally, slow pathway ablation altered conduction characteristics, pointing to complex interactions between these physiological processes.
Electrophysiology of inducible atrial flutter in patients with atrioventricular nodal reentrant tachycardia.
Clin Physiol Funct Imaging
January 2004
Article Synopsis
- * Atrial flutter was induced in 37% of AVNRT patients during testing, with shorter atrial refractory periods observed in those with inducible flutter compared to patients with a history of flutter and those without inducible flutter.
- * The findings suggest that patients with shorter atrial refractoriness are more likely to have non-clinical atrial flutter induced, indicating different underlying mechanisms for flutter and AVNRT despite their close anatomical relationship.
Article Synopsis
- - The study aimed to explore how electrical signals are transmitted from the left to right atrium in patients experiencing paroxysmal atrial fibrillation (AF).
- - Researchers mapped the right atrium of 16 patients, finding that a consistent breakthrough in electrical activity occurred near the coronary sinus (CS) entrance, with specific timing measurements noted for activations.
- - The findings suggest that the CS ostium is a key area for transseptal conduction in AF, which could be important for surgical or catheter-based treatments aimed at disrupting this pathway to manage AF.
Global dispersion of right atrial repolarization in healthy pigs and patients.
Scand Cardiovasc J
December 2003
Article Synopsis
- The study aimed to explore how effective monophasic action potential (MAP) mapping is in identifying global dispersion of atrial repolarization using the CARTO system, particularly in relation to paroxysmal atrial fibrillation (PAF).
- Researchers collected data from 10 pigs and 10 patients, revealing that those with PAF exhibited significantly greater global dispersions of MAP duration and repolarization time compared to those without PAF.
- The findings indicate that MAP mapping can effectively assess atrial repolarization dispersion, with increased dispersion potentially contributing to the development of PAF.
Article Synopsis
- * Researchers found no significant differences in activation times and conduction velocities between the AF group and the control group across various regions of the right atrium.
- * The findings imply that the previously noted conduction delay in patients with paroxysmal AF may actually occur in the posterior inter-atrial septum rather than in other areas of the right atrium.
Global repolarization sequence of the right atrium: monphasic action potential mapping in health pigs.
Pacing Clin Electrophysiol
September 2003
Article Synopsis
- The study investigated the sequence of atrial repolarization and its relationship with activation by recording endocardial monophasic action potentials (MAPs) from the right atrium of ten healthy pigs.
- Results indicated a recognizable pattern of activation that starts from the posterosuperior wall and ends at the posteroinferior wall.
- A significant positive correlation was found between repolarization time (RT) and activation time (AT), implying that as activation occurs later, repolarization takes longer, while no consistent correlation was found between MAP duration and AT.
Article Synopsis
- The main cause of paroxysmal atrial fibrillation is often an ectopic beat starting in the pulmonary veins.
- Electroanatomical mapping helps identify these triggers.
- Catheter ablation can successfully eliminate the arrhythmia, as demonstrated in two patients with triggers from different origins.
Article Synopsis
- * Measurements of local atrial fibrillation intervals (AFI) indicate that the maximum dispersion and variance of effective refractory periods were significantly higher in patients with AF compared to a control group of 12 patients without a history of AF.
- * The findings suggest that increased dispersion of atrial refractoriness, primarily due to shortened minimum AFIs, plays a crucial role in the development of paroxysmal AF.
Article Synopsis
- - The study aimed to assess the feasibility of using a modified-tip NaviStar catheter for monophasic action potential (MAP) mapping in pigs and humans.
- - MAPs were recorded at various sites in both swine and human patients, showing that the modified-tip catheter yielded significantly higher MAP amplitudes compared to the standard catheter used.
- - The findings suggest that the modified-tip NaviStar catheter is a safe and effective tool for MAP recording in clinical settings, maintaining good amplitude and baseline stability.
Article Synopsis
- Experimental studies suggest that changes in the atrial myocardium may contribute to atrial fibrillation (AF), but clinical evidence is still lacking.
- In this study, researchers measured monophasic action potentials (MAP) from patients with chronic AF (CAF) and paroxysmal AF (PAF) to assess the local atrial effective refractory period (AERP) during AF.
- Results showed that patients with CAF had significantly shorter fibrillatory intervals compared to those with PAF, indicating that the AERP is notably reduced during AF, especially in chronic cases, supporting the idea that electrical changes in the heart are linked to AF.
Article Synopsis
- The article investigates how well global dispersion of ventricular repolarization (DVR) can be estimated using data from nearby or distant heart sites.
- The study involved recording monophasic action potentials (MAP) from multiple left and right ventricular sites in pigs and patients, reconstructing repolarization maps for analysis.
- Results indicated that measurements from adjacent or remote sites significantly underestimated the global DVR, highlighting the need for a more comprehensive approach to assess ventricular repolarization accurately.
Article Synopsis
- - The study focused on how education and support after implantable cardioverter-defibrillator (ICD) surgery affect the psychosocial adjustment of patients and their families, comparing a supportive nurse-led group to a traditional physician-led education group.
- - Twenty patients (16 men and 4 women) participated, with women showing more sleep disturbances pre-ICD, and improvements were noted in health-related quality of life in the nurse-led group post-operation.
- - Results highlighted a strong need for ongoing patient education and support, as well as group meetings for emotional and informational support, particularly noting the importance of healthcare contact for post-operative adjustment.