Publications by authors named "Eva G Mulder"
Introduction: Preeclampsia, an endothelial disorder of pregnancy, predisposes to remote cardiovascular diseases (CVD). Whether there is an accelerated effect of aging on endothelial decline in former preeclamptic women is unknown. We investigated if the arterial aging regarding endothelial-dependent and -independent vascular function is more pronounced in women with a history of preeclampsia as compared to women with a history of solely normotensive gestation(s).
View Article and Find Full Text PDFObjectives: Excessive left ventricular mass (LVM) results in inefficient LV work with energy waste leading to a negative prognostic effect. We aimed at investigating the presence of inappropriate LVM and calculating the myocardial mechano-energetic efficiency index (MEEi) in former pre-eclamptic (PE) women (with or without HELLP syndrome) compared to women who experienced HELLP syndrome without PE.
Study Design: In this cross-sectional study, women with a history of normotensive HELLP (n = 32), PE without HELLP (n = 59), and PE with HELLP (n = 101) underwent echocardiography as part of the clinical CV work-up after their complicated pregnancies from 6 months to 4 years postpartum.
Article Synopsis
- Pregnancy complications like pre-eclampsia (PE) and HELLP syndrome can increase long-term risk for cardiovascular diseases, with subclinical heart issues appearing before significant problems arise.* -
- A study compared women with histories of normotensive HELLP, PE without HELLP, and PE with HELLP, using speckle-tracking echocardiography to evaluate heart function postpartum.* -
- Results indicated that women with PE and HELLP had the highest rates of abnormal heart function, highlighting the need for cardiovascular risk management in these patients.*
Article Synopsis
- The study investigates the connection between past preeclampsia and fetal growth restriction (FGR) and the risk of later cardiovascular issues, focusing on detecting early signs of heart dysfunction through speckle-tracking echocardiography.
- Researchers compared women with a history of normotensive FGR and those with preeclampsia (both with and without FGR) to assess any subclinical heart function impairment after complicated pregnancies.
- Findings suggest that both preeclampsia and normotensive FGR lead to abnormal myocardial function, indicating the need for cardiovascular risk management in these groups.
Objective: Several efforts to reduce recurrent preeclampsia have been implemented in clinical practice in the past decades. We assessed whether recurrence rates of preeclampsia and related offspring complications decreased in the past 20 years in women who received tailored preventive advices.
Study Design: In this observational cohort study, we included 752 women who had their first pregnancy complicated by preeclampsia between 1996 and 2012, and who participated in a non-pregnant risk factor assessment.
Background: Gestational diabetes mellitus (GDM) complicates 1-14% of pregnancies and relates to increased risk of adverse obstetric outcomes. Currently GDM is diagnosed using an oral glucose tolerance test (OGTT), which is burdensome and time intensive.
Objective: To compare current literature on whether the homeostatic model assessment beta cell function (HOMA-β) is an accurate predictor of an abnormal OGTT in pregnant women.