Publications by authors named "Eva Drbohlavova"
Article Synopsis
- The manuscript presents a review of haemophilia A treatment changes in adult patients in the Czech Republic from 2013 to 2021, highlighting data from the Czech National Haemophilia Programme.
- The study shows that switching from on-demand treatment to prophylaxis significantly reduced annual bleeding rates (ABR) and joint bleeding rates (AJBR) while increasing factor VIII consumption.
- With more patients on prophylaxis, the ABR decreased 6.9-fold and the AJBR decreased 8.7-fold, demonstrating the benefits of prophylactic treatment despite increased costs.
Haemophagocytic syndrome, diffuse alveolar haemorrhage, catastrophic antiphospholipid syndrome and various types of thrombotic microangiopathies are rare conditions with significant morbidity and mortality. A common feature is late diagnosis, which can affect the success of treatment. The aim of this review article is to summarize the basic diagnostic and therapeutic steps of the present subpopulation of critically ill patients.
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