Carboxymethylated and Sulfated Furcellaran from and Its Immobilization on PLA Scaffolds.

This study involved the creation of highly porous PLA scaffolds through the porogen/leaching method, utilizing polyethylene glycol as a porogen with a 75% mass ratio. The outcome achieved a highly interconnected porous structure with a thickness of 25 μm. To activate the scaffold's surface and improve its hydrophilicity, radiofrequency (RF) air plasma treatment was employed.

Renewable whey-based hydrogel with polysaccharides and polyvinyl alcohol as a soil amendment for sustainable agricultural application.

This work describes the preparation of a novel biopolymer hydrogel based on acid whey, cellulose derivatives and polyvinyl alcohol (PVA). The hydrogel was prepared and characterized with the aim of producing an environmentally-friendly soil amendment to increase water retention capacity of the soil. The findings showed considerable swelling properties of the hydrogels depending on the PVA content and crosslinking density.

Sulfation of furcellaran and its effect on hemocompatibility in vitro.

In this study, furcellaran (FUR) obtained from Furcellaria lumbricalis was firstly employed for sulfation via various methods, including SO-pyridine (SO∙Py) complex in different aprotic solvents, chlorosulfonic acid and sulfuric acid with a "coupling" reagent N,N'-Dicyclohexylcarbodiimide. Structural characterization through FT-IR, GPC, XPS and elemental analyses confirmed the successful synthesis of 6-O-sulfated FUR derivates characterized by varying degrees of sulfation (DS) ranging from 0.15 to 0.

Design and Fabrication of Electrospun PLA-Based Silica-Modified Composite Nanofibers with Antibacterial Properties for Perspective Wound Treatment.

The aim of this study was to develop a novel amikacin (AMI) delivery system with prolonged release based on composite electrospun nanofibers of PLA supplemented with AMI-loaded Si nanoparticles of different morphology. The resultant materials were characterized in terms of their physical properties (scanning electron microscopy, Brunauer-Emmett-Teller analysis, thermogravimetric analysis, water contact angle). High-Performance Liquid Chromatography was used to determine the AMI content in the liquid fractions obtained from the release study.

Antibacterial Porous Systems Based on Polylactide Loaded with Amikacin.

Three porous matrices based on poly(lactic acid) are proposed herein for the controlled release of amikacin. The materials were fabricated by the method of spraying a surface liquid. Description is given as to the possibility of employing a modifier, such as a silica nanocarrier, for prolonging the release of amikacin, in addition to using chitosan to improve the properties of the materials, e.

Unravelling the highly efficient synthesis of individual carbon nanodots from casein micelles and the origin of their competitive constant-blue-red wavelength shift luminescence mechanism for versatile applications.

Synthesis of casein-derived carbon nanodots (CND) using a microwave-assisted approach, giving a high product yield (25%), is reported. Casein was used as a sustainable carbon source, and polyvinylpyrrolidone was used as a stabilizer for the nanodots. The size of the prepared amorphous CND corresponds to individual casein coils, which were only partially carbonized.

Eco-friendly whey/polysaccharide-based hydrogel with poly(lactic acid) for improvement of agricultural soil quality and plant growth.

A set of renewable and biodegradable hydrogels based on acid whey and cellulose derivatives blended with poly(lactic acid) (PLA) were designed as eco-friendly biopolymeric material for sustainable agricultural applications. The physico-chemical properties of the hydrogel were evaluated using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and rheological measurements. The effect of the whey/polysaccharide/PLA hydrogel on soil quality improvement (water retention study, biodegradability, loading capacity and release of the fertilizers) and the growth pattern of Raphanus sativus and Phaseolus vulgaris has been also studied.

Investigation of arsenic removal from aqueous solution through selective sorption and nanofiber-based filters.

Background: This research paper focuses on removing of arsenic from contaminated water via a nanofibrous polymeric microfiltration membrane, applied in prospective combination with an inorganic sorbent based on iron oxide hydroxide FeO(OH).

Materials And Methods: Nanofibrous materials were prepared by electrospinning from polyurethane selected by an adsorption test. The chemical composition (FTIR), morphology (SEM, porometry) and hydrophilicity (contact angle) of the prepared nanostructured material were characterized.

Encapsulation of Amikacin into Microparticles Based on Low-Molecular-Weight Poly(lactic acid) and Poly(lactic acid--polyethylene glycol).

The aim of this study was to fabricate novel microparticles (MPs) for efficient and long-term delivery of amikacin (AMI). The emulsification method proposed for encapsulating AMI employed low-molecular-weight poly(lactic acid) (PLA) and poly(lactic acid--polyethylene glycol) (PLA-PEG), both supplemented with poly(vinyl alcohol) (PVA). The diameters of the particles obtained were determined as less than 30 μm.

Nanoparticle-Based Rifampicin Delivery System Development.

The alkaline milieu of chronic wounds severely impairs the therapeutic effect of antibiotics, such as rifampicin; as such, the development of new drugs, or the smart delivery of existing drugs, is required. Herein, two innovative polyelectrolyte nanoparticles (PENs), composed of an amphiphilic chitosan core and a polycationic shell, were synthesized at alkaline pH, and in vitro performances were assessed by H NMR, elemental analysis, FT-IR, XRD, DSC, DLS, SEM, TEM, UV/Vis spectrophotometry, and HPLC. According to the results, the nanostructures exhibited different morphologies but similar physicochemical properties and release profiles.