Synergistic effect of essential oils and chlorhexidine against planktonic and biofilm-forming cells of .

() , is often associated with secondary infection of the skin and external auditory canal in dogs and cats. The treatment of infections is based on the local application of antifungals often combined with antiseptics. Due to increased resistance of yeast to commonly used antimycotics, especially in biofilm-forming cells, the use of natural substances, e.

Extracellular phospholipase production by Malassezia pachydermatis strains and its inhibition by selected antimycotics and plant essential oil components.

Extracellular phospholipase (EPL) plays an important role in the pathogenesis of the yeast Malassezia pachydermatis. Currently, the attention of researchers is focused on studying the virulence factors involved in this process and searching solutions to reduce their activity. One of the options is the use of natural remedies as anti-virulence agents.

Biofilm Formation in Medically Important Species.

Worldwide, the number of infections caused by biofilm-forming fungal pathogens is very high. In human medicine, there is an increasing proportion of immunocompromised patients with prolonged hospitalization, and patients with long-term inserted drains, cannulas, catheters, tubes, or other artificial devices, that exhibit a predisposition for colonization by biofilm-forming yeasts. A high percentage of mortality is due to candidemia caused by medically important species.

In Vitro Biofilm Formation by Isolates and Its Susceptibility to Azole Antifungals.

The yeast , an opportunistic pathogen that inhabits the skin of various domestic and wild animals, is capable of producing a biofilm that plays an important role in antifungal resistance. The aim of this research study was to find the intensity of biofilm production by strains isolated from the ear canal of healthy dogs, and to determine the susceptibility of planktonic, adhered and biofilm-forming cells to three azole antifungals-itraco-nazole, voriconazole and posaconazole-that are most commonly used to treat infections. Out of 52 isolates, 43 strains (82.

Fungal Flora in Asymptomatic Pet Guinea Pigs and Rabbits.

Fungal skin diseases are well-recognized diseases with public health implications. The study provides a comprehensive overview and aims to determine the rate of positive fungal cultures to identify the most common fungal species in guinea pigs and rabbits and to determine the rate of asymptomatic carriers in healthy pet animals. This knowledge is essential for understanding disease transmission dynamics and epidemiological situation problems.

Comparison of antifungal activity of selected essential oils against .

Introduction: Fusaria are microscopic filamentous fungi which are spread in soil, in various organic substrates, and include more than 80 phytopathogenic species which are predominantly hosted by cereals, fruits and vegetables. Many of these species, under certain conditions, are capable of synthesizing secondary metabolites, mycotoxins. At present, various substances are used for their elimination and one of the solutions appears to be essential oils.

Antibiofilm activity of selected plant essential oils from the family against clinical isolates.

Introduction: The virulence of is conditioned by several virulence factors, one of which is the formation of biofilm which reduces the sensitivity of the yeast to conventional antimycotics. This study determines the antifungal and antibiofilm activity of five essential oils (EOs) of the family: , , , , and .

Material And Methods: In the preliminary research, the antifungal effect of eachof the EOs was tested in the concentration range of 200-0.

[Synergistic effect of azole antimycotics (clotrimazole and fluconazole) and natural substances].

Nowadays the treatment of fungal infections is difficult due to increasing resistance of fungal pathogens to antimycotics. The efficacy of antimycotics can be increased by a proper combination of commercial drugs and natural substances. The 100% antimycotic activity was found using susceptibility testing of Candida albicans yeasts on clotrimazole alone and in combination with tea tree oil, or with a multicomponent preparation containing cannabis oil and various essential oils and in combination with propolis tincture.

Species composition of Malassezia yeasts in dogs in Slovakia.

Malassezia (M.) pachydermatis is the lipophilic yeast, which is normally present on the skin and in the ear canal of dogs but under certain conditions it may cause dermatitis and otitis. There is less known about the occurrence of lipid-dependent Malassezia species in dogs.

Microbial binding and biodegradation of mycotoxins.

This contribution provides an overview of literature data on the microbial binding and biodegradation of mycotoxins. These data and preliminary results from our own laboratory suggest that mycotoxin-bacterial binding or biodegradation is a realistic process and encourages the screening of bacterial strains and their biodegradation potential.