Publications by authors named "Eva Bjerre Ostenfeld"

Article Synopsis
  • Active surveillance for cervical intraepithelial neoplasia grade 2 (CIN2) has been increasingly used in Denmark, focusing on women of reproductive age, and aims to evaluate clinical and socioeconomic factors influencing management methods.
  • A nationwide study analyzed data from 27,536 women diagnosed with CIN2 between 1998 and 2020, revealing that younger, HPV-vaccinated women were more likely to undergo active surveillance compared to those who had a large loop excision (LLETZ).
  • The trend showed a significant rise in active surveillance from 21.7% in 2004 to 73.6% in 2019, although the proportion of younger women opting for this method decreased over time.
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The aim of this study was to evaluate the effect of an acute bout of cycling immediately after oral glucose intake on glucose metabolism in pregnant women at risk for gestational diabetes mellitus (GDM). Fifteen pregnant women with BMI ≥ 27 kg/m were enrolled in a randomized crossover controlled study and underwent two oral glucose tolerance tests (OGTTs) ingesting 75 g of glucose followed by either 20 min of stationary cycling at moderate intensity (65%-75% maximal heart rate) or rest. Using continuous glucose monitors, glucose was measured up to 48 h after the OGTT.

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In this review, we discuss genital herpes - a common sexually transmitted infection, which can be transmitted to the baby during birth. Neonatal herpes is a rare but serious infection. In 2019, the Danish Society of Obstetrics and Gynecology revised the guideline for management of genital herpes in pregnancy.

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Background: Recurrence is a common outcome among patients that have undergone an intended curative resection for colorectal cancer. However, data on factors that influence colorectal cancer recurrence are sparse. We report descriptive characteristics of both colon and rectal cancer recurrence in an unselected population.

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Objective: To examine whether preadmission glucocorticoid use increases the risk of anastomotic leakage after colon and rectal cancer resections.

Design: A population-based cohort study.

Setting: Denmark (2001-2011).

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Purpose: Persistent cervical infection with human papillomavirus (HPV) may be a marker of poor immune function and thus associated with an increased cancer risk. HPV infection is implicated in all cases of cervical cancer, but except for anal and esophageal cancers, the association between persistent HPV infection and gastrointestinal cancer has not been investigated.

Methods: We performed a nationwide population-based cohort study of 83,008 women undergoing cervical conization between 1978 and 2011, using cervical conization as a marker of chronic HPV infection.

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Objective: To evaluate recent trends in the prevalence and impact of comorbidity on colorectal cancer (CRC) survival in the Central Region of Denmark.

Material And Methods: Using the Danish National Registry of Patients, we identified 5,777 and 2,964 patients with a primary colon or rectal cancer, respectively, from 2000 through 2011. We estimated survival according to Charlson Comorbidity Index scores and computed mortality rate ratios (MRRs) using Cox proportional hazard regression analysis, adjusting for age and sex.

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Objective: To explore the completeness of tumor, node, metastasis (TNM) staging for colon and rectal cancer in the Danish Cancer Registry.

Material And Methods: From the Danish Cancer Registry, we retrieved data on TNM stage, year of diagnosis, sex, and age for 15,976 and 8292 patients, respectively, with first diagnoses of colon or rectal cancer during the 2004–2009 period. From the Danish National Patient Register, we retrieved data on comorbidity (computed as Charlson Comorbidity Index scores).

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