The hippocampus's vulnerability to trauma-induced stress can lead to pathophysiological disturbances that precipitate the development of posttraumatic stress disorder (PTSD). The mechanisms of resilience that foster remission and mitigate the adverse effects of stress remain unknown. We analyzed the evolution of hippocampal morphology between 2016/2017 and 2018/2019, as well as the memory control mechanisms crucial for trauma resilience.
View Article and Find Full Text PDFHealthy aging is characterized by frontal and diffuse brain changes, while certain age-related pathologies such as semantic dementia will be associated with more focal brain lesions, particularly in the temporo-parietal regions. These changes in structural integrity could influence functional brain networks. Here we use multilayer brain network analysis on structural (DWI) and functional (fMRI) data in younger and older healthy individuals and patients with semantic dementia.
View Article and Find Full Text PDFIntroduction: Individuals suffering from PTSD recount the traumatic event using perceptual, emotional and sensory details. Memorization and recall of individual events are influenced by the individual's social function, i.e.
View Article and Find Full Text PDFThe study of the links between episodic memory (memory of personal experiences) and semantic memory (memory of general knowledge about the world, others, and oneself) has played a significant role in psychology and neuroscience research for several decades. The way memories lose specificity and become semantized over time, and how these two major memory systems interact to represent the individual in the social world and allow to project themselves into the future, are particularly fascinating themes in understanding the mechanisms of autobiographical memory. Numerous studies rely on various memory pathologies, primarily amnesic syndromes but also other disorders where memory impairment is not the main symptom, such as autism spectrum disorders.
View Article and Find Full Text PDFObjective: To study karyotypes of >8,200 oocyte donor candidates in nulliparous or multiparous women compared with a reference population.
Design: A retrospective observational multicentric study.
Setting: University Hospital Centers.
Gynecol Obstet Fertil Senol
January 2025
Objectives: Healthy age-related cognitive changes are highly heterogeneous across individuals. This variability is increasingly explained through the lens of spontaneous fluctuations of brain activity, now considered a powerful index of age-related changes. However, brain activity is a biological process modulated by circadian rhythms, and how these fluctuations evolve throughout the day is under investigation.
View Article and Find Full Text PDFThe ability to organize and memorize the unfolding of events over time is a fundamental feature of cognition, which develops concurrently with the maturation of the brain. Nonetheless, how temporal processing evolves across the lifetime as well as the links with the underlying neural substrates remains unclear. Here, we intend to retrace the main developmental stages of brain structure, function, and cognition linked to the emergence of timing abilities.
View Article and Find Full Text PDFBackground: Patients with breast cancer (BC) exhibit circadian rhythm disruptions, mainly of rest-activity rhythm (RAR), of which sleep is an essential component, and cortisol rhythm. Sleep complaints such as insomnia and cognitive impairments are prevalent in BC. In general population, sleep is known to contribute greatly to cognition.
View Article and Find Full Text PDFThe words people use in everyday life tell us about their emotions, their mental state and allow us to understand how people process and interpret an event. Previous research has established a link between the content analysis of narrative texts and the psychopathology of people who have experienced trauma. This study examines whether the development of PTSD following exposure to a previous traumatic event alters the way people express themselves in the context of an anxiety-provoking event, the COVID-19 pandemic.
View Article and Find Full Text PDFAromatase inhibitors (AIs) are associated with sleep difficulties in breast cancer (BC) patients. Sleep is known to favor memory consolidation through the occurrence of specific oscillations, i.e.
View Article and Find Full Text PDFThe experience of an extremely aversive event can produce enduring deleterious behavioral, and neural consequences, among which posttraumatic stress disorder (PTSD) is a representative example. Although adolescence is a period of great exposure to potentially traumatic events, the effects of trauma during adolescence remain understudied in clinical neuroscience. In this exploratory work, we aim to study the whole-cortex functional organization of 14 adolescents with PTSD using a data-driven method tailored to our population of interest.
View Article and Find Full Text PDFThe present study was based on empirical data collected during the first phase (2016) of Study 1000, part of the 13-November Program: a corpus of 934 individual interviews conducted 6-11 months after the events. To process this empirical material, the authors used integrated TXM software, which provides several classic textometry tools. They mainly used the lexical specificity analysis tool, which statistically measures the irregularity of the word distribution according to the parts of the corpus.
View Article and Find Full Text PDFPost-traumatic stress disorder (PTSD) lacks clear biomarkers in clinical practice. Language as a potential diagnostic biomarker for PTSD is investigated in this study. We analyze an original cohort of 148 individuals exposed to the November 13, 2015, terrorist attacks in Paris.
View Article and Find Full Text PDFBackground: People with neurodegenerative diseases may have difficulty learning new information, owing to their cognitive impairments. Teaching them techniques for learning in social contexts could alleviate this difficulty. The present study will examine the performances of patients with Alzheimer's disease and patients with the semantic variant of primary progressive aphasia on a memory test administered in three social contexts.
View Article and Find Full Text PDFObjective: To study the fertility outcomes of women who tried to conceive after breast cancer (BC) treatment and fertility preservation.
Design: Retrospective observational, bicentric cohort study.
Setting: University hospital.
Background: When faced with a surge of physically injured individuals, especially following a traumatic event like an attack, frontline practitioners prioritize early triage. Detecting potential psychological injuries soon after such events remains challenging. Some individuals might develop post-traumatic stress disorder (PTSD) according to DSM-V criteria.
View Article and Find Full Text PDFBrain structure and function are intimately linked, however this association remains poorly understood and the complexity of this relationship has remained understudied. Healthy aging is characterised by heterogenous levels of structural integrity changes that influence functional network dynamics. Here, we use the multilayer brain network analysis on structural (diffusion weighted imaging) and functional (magnetoencephalography) data from the Cam-CAN database.
View Article and Find Full Text PDFNEUROPSYCHOLOGY OF MEMORY. In neuropsychology, memory is shown as a complex function composed of several memory systems. Five memory systems are proposed: working memory (or short term memory), episodic memory, semantic memory, perceptive memory, and procedural memory.
View Article and Find Full Text PDFThe mathematical study of human memory is still an open challenge. Cognitive psychology and neuroscience have given a big contribution to understand how the human memory is structured and works. Cognitive psychologists developed experimental paradigms, conceived quantitative measures of performance in memory tasks for both healthy people and patients with memory disorders, but in terms of mathematical modeling human memory there is still a lot to do.
View Article and Find Full Text PDFBackground: Many patients treated for breast cancer (BC) complain about cognitive difficulties affecting their daily lives. Recently, sleep disturbances and circadian rhythm disruptions have been brought to the fore as potential contributors to cognitive difficulties in patients with BC. Yet, studies on these factors as well as their neural correlates are scarce.
View Article and Find Full Text PDFIntroduction: Reminiscence therapy (RT), which engages individuals to evoke positive memories, has been shown to be effective in improving psychological well-being in older adults suffering from PTSD, depression, and anxiety. However, its impact on brain function has yet to be determined. This paper presents functional magnetic resonance imaging (fMRI) data to describe changes in autobiographical memory networks (AMN) in community-dwelling older adults.
View Article and Find Full Text PDFFollowing a long period of neglect, research on different facets of collective memory is now developing apace in the human and social sciences, as well as at their interface with psychology and neuroscience. This resolutely multidisciplinary renewal of interest in memory sciences has given rise to a plethora of concepts with diverse meanings (e.g.
View Article and Find Full Text PDF