Inhibition of hydrogen peroxide-induced senescence markers by yeast-derived vacuoles in human lung fibroblasts.

Senescence significantly contributes to aging in various tissues, influenced by factors such as lysosomal alkalinization, which disrupts autophagic flux and accumulates toxic substances. This disruption leads to oxidative stress, increased lysosomal permeability, cellular senescence, and apoptosis. Similar to mammalian lysosomes, S.

Spent coffee ground disrupts Listeria monocytogenes biofilm formation through inhibition of motility and adhesion via quorum sensing regulation.

Spent coffee grounds (SCGs) have been explored for use as various bioresources, such as biofuels, and are known to possess biological functions, including antioxidant activity. However, the antibiofilm properties of SCGs against pathogenic bacteria have not been fully investigated. Therefore, this study aimed to highlight the inhibitory effects of SCG extract (SCGE) on biofilm formation in Listeria monocytogenes and investigated the underlying mechanisms.