Publications by authors named "Eunsil Ko"
Objective: This study aimed to identify and analyze the factors influencing Emergency Department Length of Stay (ED LOS) using a nationwide database to improve emergency care efficiency.
Methods: This retrospective study utilized data from the National Emergency Department Information System (NEDIS) in South Korea, covering 25,578,263 ED visits from 2018 to 2022. Patient demographics, clinical characteristics, and ED operational variables were examined.
Article Synopsis
- - The study analyzed 326 hemodialysis patients with COVID-19 to assess how chest CT findings could predict mortality related to the disease.
- - Key CT findings linked to higher mortality included lung involvement greater than 2.7%, pleural effusion, nodular consolidation, and patchy infiltration, with over 21% of patients dying during hospitalization.
- - AI-assisted CT analysis effectively quantified lung involvement and revealed that even minor lung issues could lead to increased mortality, emphasizing the importance of CT findings in this vulnerable patient population.
Background: Various scoring systems are utilized to assess severe trauma patients, with one of the most commonly used tools being the International Classification of Diseases Injury Severity Score (ICISS) criteria derived from the Survival Risk Ratio (SRR) calculated using diagnostic codes. This study aimed to redefine the severe trauma scoring system in Korea based on the SRR for diagnostic codes, and subsequently evaluate its performance in predicting survival outcomes for trauma patients.
Methods: This study included trauma patients who visited Level 1 and 2 emergency departments (EDs) between January 2016 and December 2019, utilizing the Korean National Emergency Department Information System (NEDIS) database.
Effectiveness of regdanvimab on mortality in COVID-19 infected patients on hemodialysis.
Kidney Res Clin Pract
January 2024
Article Synopsis
- - The study investigated the effectiveness of regdanvimab in reducing mortality among COVID-19 patients with end-stage renal disease undergoing hemodialysis, comparing those treated with the drug to those who were not.
- - Among the 230 patients studied, the group receiving regdanvimab had a significantly lower in-hospital mortality rate (13.0%) compared to the non-regdanvimab group (32.0%).
- - Results suggested that regdanvimab could be a beneficial treatment option for these patients, especially considering their high risk of severe infection and mortality.
Article Synopsis
- The study examined how the COVID-19 pandemic impacted emergency department (ED) visits for emergency care-sensitive conditions (ECSCs) in Korea from 2019 to 2021.
- Overall, total ED visits dropped by about 23% during the pandemic, but visits for cardiac arrest increased, while those for other ECSCs like intracranial injuries, ischemic heart disease, and stroke initially decreased before returning to pre-pandemic levels in 2021.
- The findings indicate a rising proportion of ECSCs in total ED visits over the pandemic period, suggesting that while overall ED visits declined, certain critical conditions became more pronounced.
Objective: : With general aging of the population, emergency department (ED) utilization by elderly patients is increasing. In this study, we analyzed data on ED visits of patients aged 65 years and older in Korea.
Methods: : The study is a retrospective analysis of National Emergency Department Information System (NEDIS) data from 2018-2022, focusing on patients aged 65 years and older who visited EDs across Korea.
Objective: : As of 2018, approximately 1.2 million pediatric patients visited emergency departments (EDs) in Korea, showing a steady increase. Given the distinct differences between children and adults, it is vital to examine the epidemiological characteristics of pediatric patients visiting the ED.
View Article and Find Full Text PDFObjective: : This study analyzed trends in emergency department (ED) visits in South Korea using the National Emergency Department Information System (NEDIS) data from 2018 to 2022.
Methods: : This was a retrospective observational study using data from the NEDIS database from 2018 to 2022. Age- and sex-standardized ED visits per 100,000 population, as well as age- and sex-standardized rates for mortality, admission, and transfer, were calculated.
Background: Since 2014, Korea has been operating the National Emergency Medical Situation Room (NEMSR) to provide regional emergency departments (EDs) with coordination services for the interhospital transfer of critically ill patients. The present study aimed to describe the NEMSR's experience and interhospital transfer pattern from EDs nationwide, and investigate the factors related to delayed transfers or transfers that could not be arranged by the NEMSR.
Methods: This study was a retrospective cross-sectional analysis of the NEMSR's coordination registry from 2017 to 2019.
The need of palliative care at the end-of-life in the emergency departments (ED) is growing. The study aims to investigate the epidemiology of patients who died during care in ED using nationwide database, and to estimate the need for palliative care in the ED. A retrospective observational study was conducted using the National Emergency Department Information System (NEDIS) database.
View Article and Find Full Text PDFBackground: Prolonged emergency department length of stay (EDLOS) in critically ill patients leads to increased mortality. This nationwide study investigated patient and hospital characteristics associated with prolonged EDLOS and in-hospital mortality in adult patients admitted from the emergency department (ED) to the intensive care unit (ICU).
Methods: We conducted a retrospective cohort study using data from the National Emergency Department Information System.
COVID-19-related clinical outcomes among Korean hemodialysis patients.
Kidney Res Clin Pract
September 2022
Background: Hemodialysis (HD) patients are more vulnerable to viral epidemics, experiencing higher mortality rates compared to individuals without chronic kidney disease (CKD). This retrospective cohort study sought to demonstrate clinical outcomes and associated factors among coronavirus disease 2019 (COVID-19) confirmed Korean HD patients.
Methods: From February 2020 to November 2021, the COVID-19 Task Force Team collected clinical data for HD patients with confirmed COVID-19 via a self-report survey of nephrologists.
Article Synopsis
- Ginsenosides, key components of ginseng, were studied for their ability to modulate immune responses, specifically through a ginseng product called GBCK10S made from enzymatic bioconversion.
- The study involved testing GBCK10S on mice and a human NK cell line to assess its effects on immune markers and cell activities using various scientific methods.
- Results showed that GBCK10S boosted levels of specific immune proteins and activated natural killer cells, suggesting it has strong potential to enhance immune response mediated by different types of immune cells.
Article Synopsis
- Plant tissue culture can be used to produce secondary metabolites that may have therapeutic benefits, particularly in treating skin issues like photoaging and pigmentation.
- Researchers tested the effects of callus pellet extract (AYC-P-E) on melanogenesis in B16F10 melanoma cells after inducing excessive melanin production.
- AYC-P-E showed a significant inhibition of melanin production in cell studies and led to measurable improvements in skin pigmentation in clinical trials, linked to the activation of specific signaling pathways (MEK/ERK and AKT).
Article Synopsis
- The extract has demonstrated multiple health benefits, including anti-inflammatory and antioxidant effects, but its commercial production is time-consuming and environmentally challenging.
- Researchers are developing a bioreactor system to produce the extract rapidly from cultured callus to test its efficacy against photoaging in skin cells exposed to UVB light.
- The study identified 17 key metabolites in the extract that significantly enhance skin cell recovery, collagen production, and moisture retention while mitigating inflammation associated with skin damage from UVB exposure, indicating its potential as a cosmetic ingredient.
Objective: Coronary angiography (CAG) for survivors of out-of-hospital cardiac arrest (OHCA) enables early identification of coronary artery disease and revascularization, which might improve clinical outcome. However, little is known for the role of CAG in patients with initial non-shockable cardiac rhythm.
Methods: We investigated clinical outcomes of successfully resuscitated 670 adult OHCA patients who were transferred to 27 hospitals in Cardiac Arrest Pursuit Trial with Unique Registration and Epidemiologic Surveillance (CAPTURES), a Korean nationwide multicenter registry.
A febrile respiratory infectious disease unit (FRIDU) with a negative pressure ventilation system was constructed outside the emergency department (ED) of the Samsung Medical Center in 2015, to screen for patients with contagious diseases requiring isolation. We evaluated the utility of the FRIDU during 1 year of operation. We analyzed 1,562 patients who were hospitalized after FRIDU screening between August 2015 and July 2016.
View Article and Find Full Text PDFObjective: Acute myocardial infarction is a major cause of out-of-hospital cardiac arrest (OHCA). Coronary angiography (CAG) enables diagnostic confirmation of coronary artery disease and subsequent revascularization, which might improve the prognosis of OHCA survivors. Non-randomized data has shown a favorable impact of CAG on prognosis for this population.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers developed a probiotic-fermented version of red ginseng and tested it on mice with colitis, finding it significantly reduced the severity of the condition compared to regular ginseng or probiotics alone.
- * The probiotic-fermented red ginseng also lowered levels of inflammatory biomarkers in the serum and colorectal tissues, indicating that it could serve as a consistently effective treatment for colitis.
Context: Red ginseng (heat-processed Panax ginseng) is a well-known alternative medicine with pharmacological antidiabetic activity. It exerts pharmacological effects through the transformation of saponin into metabolites by the intestinal microbiota. Given that intestinal conditions and intestinal microflora vary among individuals, the pharmacological effects of orally administered red ginseng likely may vary among individuals.
View Article and Find Full Text PDFMassive pulmonary embolism (MPE) with hemodynamic instability is a clinical condition with a poor prognosis and high mortality rates. There are no definitive treatment options for cardiac arrest due to MPE. A 52-year-old female presented at our emergency department with cardiac arrest, and a 62-year-old female presented after achieving return of spontaneous circulation of cardiac arrest from a local hospital, respectively.
View Article and Find Full Text PDFAim: We aimed to evaluate the prognostic value of optic nerve sheath diameter (ONSD) and grey-to-white matter (GWR) either alone or in combination in patients treated with targeted temperature management (TTM) after cardiac arrest (CA).
Methods: We conducted a retrospective single centre study of post cardiac arrest patients treated with TTM. ONSD and GWR on brain computed tomography (CT) was measured by two emergency physicians.