and mutation-related spondylocarpotarsal synostosis: a case report.

Spondylocarpotarsal synostosis syndrome (SCTS) is a rare genetic disorder characterized by vertebral fusion, short stature, and skeletal anomalies. SCTS is primarily associated with mutations in filamin B. However, in this report, we present a unique case of SCTS in a 28-year-old male who complained of neck and shoulder pain persisting for 1 year.

Risk of Contrast-Induced Acute Kidney Injury in Computed Tomography: A 16 Institutional Retrospective Cohort Study.

Objectives: Concern about contrast-induced acute kidney injury (CI-AKI) may delay the timely administration of contrast media for computed tomography (CT). The precise causative effect of iodinated contrast media on CI-AKI and its relevant risk factors remains an area of ongoing investigation. Therefore, this study aimed to determine the risk of CI-AKI following contrast-enhanced CT and its predisposing risk factors.

The Contribution of Neutrophil Extracellular Traps to Coagulopathy in Patients with COVID-19-Related Thrombosis.

COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is associated with hypercoagulability and increased incidence of thrombotic events. In this study, we investigated the levels of neutrophil extracellular trap biomarkers and von Willebrand factor to assess if these could predict the occurrence of a thrombotic event in COVID-19 patients. We enrolled 202 patients hospitalized with symptomatic COVID-19 infection.

Optimal timing of chemoradiation after resection or biopsy of glioblastomas: a nationwide population-based study.

Background: This study investigated the optimal timing of concurrent chemoradiotherapy (CCRT) following surgery for patients with newly diagnosed glioblastoma (GBM). The focus was on understanding whether the interval between surgery and CCRT impacts survival outcomes.

Methods: Data from the Korean National Health Insurance Research Database ( https://opendata.

Are Experiences of Discrimination Associated With Views of Physical Activity and Climate Policy Support in Canada?

Background: Social climate refers to the general feelings, norms, and opinions in a society and may be affected by experiences of discrimination. This study examined whether experiences of discrimination are associated with the social climate of physical (in)activity and support for policies addressing dual benefits of physical activity (PA) and climate change.

Methods: Data from the 2023 Social Climate Survey were used (n = 1950; ≥18 y).

Global trends in importance of 24-hour movement behaviors to pediatric health: Implications for South Korea.

Cultivating a 24-hour movement behavioral profile conducive to health and well-being, marked by adequate levels of physical activity, limited screen time, and sufficient sleep, has emerged as an important avenue for promoting pediatric health. We aimed to provide evidence of this potential, this multiphase, multimethod, and integrative review comprehensively investigated the global trends in health promotion initiatives and status of the Korean pediatric population. This integrative review comprised three phases employing various review methods: an environmental scan of existing guidelines for 24-hour movement behaviors worldwide, a rapid review of physical activity-related indicators from Global Matrix data, and a systematic review of 24-hour movement behaviors among children and adolescents in South Korea.

The relevance of the United Nations' Sustainable Development Goals in the promotion of sport, physical activity, and recreation in Canada.

Canada is unique in that it has established four national strategies in support of sport, physical activity, and/or recreation (SPAR). Though some of these strategies identify potential social and environmental correlates of SPAR, and articulate societal outcomes such as changes in behaviour and health, there are no explicit links to larger global initiatives such as the United Nations' Sustainable Development Goals (SDGs). Given that countries are expected to propose a plan for addressing the 17 SDGs, and that obvious overlap exists between several of the proposed development goals and SPAR, Canada should consider whether common indicators can be identified across these strategies and the SDGs simultaneously to facilitate more efficient and effective action.

Assessing the Efficacy of Medical and Cultural Support for Immigrant Adaptation and Social Integration.

Background: The research was designed to investigate the perceptions and attitudes of immigrants towards extra medical support programs that Immigrant Support Centers (ISC) offer. We aimed to find how they evaluate such medical support in terms of helpfulness for social integration in the host country.

Methods: The study was performed in South Korea during May-June 2023.

Physical Activity Report Card Indicators and the United Nations Sustainable Development Goals: Insights From Global Matrix 4.0.

Background: The World Health Organization recognizes that physical activity (PA) during childhood is crucial for healthy development, aligning well with the achievement of several United Nations (UN) Sustainable Development Goals (SDGs). This study aimed to explore the associations between 10 key indicators of PA for children and adolescents assessed in the Global Matrix 4.0 project, and the UN SDGs.

Effects of mixed metal exposure on MRI metrics in basal ganglia.

Welding fumes contain various metals. Past studies, however, mainly focused on Manganese (Mn)-related neurotoxicity. This study investigated welding-related mixed metal exposure effects on MRI metrics in the basal ganglia (BG) and their dose-response relationship.

Scalable Low-Temperature CO Electrolysis: Current Status and Outlook.

The electrochemical CO reduction (eCOR) in membrane electrode assemblies (MEAs) has brought e-chemical production one step closer to commercialization because of its advantages of minimized ohmic resistance and stackability. However, the current performance of reported eCOR in MEAs is still far below the threshold for economic feasibility where low overall cell voltage (<2 V) and extensive stability (>5 years) are required. Furthermore, while the production cost of e-chemicals heavily relies on the carbon capture and product separation processes, these areas have received much less attention compared to CO electrolysis, itself.

Mosaic ablation of pancreatic β cells induces de-differentiation and repetitive proliferation of residual β cells in adult mice.

Diabetes mellitus is induced by quantitative and qualitative decline in pancreatic β cells. Although its radical therapy has not yet been established, β cell regeneration is a promising option. We investigate here two mouse models of β cell regeneration induced after ∼80% reduction in β cell number: Cre/loxP-mediated β cell ablation and partial pancreatectomy.

Effect of cations on aerobic granulation for sidestream treatment.

Aerobic granular sludge (AGS) represents an aggregate of sludge formed through the self-immobilization of microorganisms under aerobic conditions. It is currently under scrutiny for its potential as a technology to reduce carbon emissions and promote sustainability. The practicality of AGS stems from its ability to encourage granule formation and enhance structural stability.

Identification of novel anti-obesity saponins from the ovary of sea cucumber ().

The potential anti-obesity effects of sea cucumber extract have been reported. However, the individual saponins responsible for these effects are yet to be isolated and characterized. This study aimed to identify the most effective sea cucumber body part for inhibiting lipid accumulation in adipocytes and to elucidate the compounds responsible for this effect using nuclear magnetic resonance (NMR) techniques.

Association between Levetiracetam Use and Survival in Patients with Glioblastoma: A Nationwide Population-Based Study.

Purpose: This study aimed to investigate whether levetiracetam (LEV), the most used antiepileptic drug, influences survival in patients with glioblastoma (GBM), using a national database.

Materials And Methods: This study used data from the Korea Health Insurance Review and Assessment database. Patients diagnosed with GBM between 2007-2018 treated with standard therapy were included.

Effect of settling time and organic loading rates on aerobic granulation processes treating high strength wastewater.

Despite its numerous advantages, the aerobic granular sludge (AGS) process faces several challenges that hinder its widespread implementation. One such challenge is the requirement for high organic load ratios (OLR), which significantly impacts AGS formation and stability, posing a barrier to commercialization. In response to these challenges, this study investigates the granulation and treatment efficacy of the AGS process for treating high-concentration wastewater under various OLR and settling time.

Bevacizumab Alone Versus Bevacizumab Plus Irinotecan in Patients With Recurrent Glioblastoma: A Nationwide Population-Based Study.

Background: For treating recurrent glioblastoma, for which there is no established treatment, the antiangiogenic antibody, bevacizumab, is used alone or with irinotecan. This study was aimed at comparing the survival of patients with recurrent glioblastoma receiving bevacizumab monotherapy and those receiving bevacizumab plus irinotecan combination therapy (B+I) by using a nationwide population-based dataset.

Methods: Patients matching the International Classification of Diseases code C71.

Exploring the Interplay Between Climate Change, 24-Hour Movement Behavior, and Health: A Systematic Review.

Background: Given the emergence of climate change and health risks, this review examined potential relationships between varying indicators of climate change, movement behaviors (ie, physical activity [PA], sedentary behavior, and sleep), and health.

Methods: Seven databases were searched in March 2020, April 2023, and April 2024. To be included, studies must have examined indicators of climate change and at least one of the movement behaviors as either an exposure or a third variable (ie, mediator/moderator), and a measure of health as outcome.