Technical Note: Mobile accelerator guidance using an optical tracker during docking in IOERT procedures.

Purpose: Intraoperative electron radiation therapy (IOERT) involves the delivery of a high radiation dose during tumor resection in a shorter time than other radiation techniques, thus improving local control of tumors. However, a linear accelerator device is needed to produce the beam safely. Mobile linear accelerators have been designed as dedicated units that can be moved into the operating room and deliver radiation in situ.

ConoSurf: Open-source 3D scanning system based on a conoscopic holography device for acquiring surgical surfaces.

Background: A difficulty in computer-assisted interventions is acquiring the patient's anatomy intraoperatively. Standard modalities have several limitations: low image quality (ultrasound), radiation exposure (computed tomography) or high costs (magnetic resonance imaging). An alternative approach uses a tracked pointer; however, the pointer causes tissue deformation and requires sterilizing.

Assessment of intraoperative 3D imaging alternatives for IOERT dose estimation.

Intraoperative electron radiation therapy (IOERT) involves irradiation of an unresected tumour or a post-resection tumour bed. The dose distribution is calculated from a preoperative computed tomography (CT) study acquired using a CT simulator. However, differences between the actual IOERT field and that calculated from the preoperative study arise as a result of patient position, surgical access, tumour resection and the IOERT set-up.

A Novel Prior- and Motion-Based Compressed Sensing Method for Small-Animal Respiratory Gated CT.

Low-dose protocols for respiratory gating in cardiothoracic small-animal imaging lead to streak artifacts in the images reconstructed with a Feldkamp-Davis-Kress (FDK) method. We propose a novel prior- and motion-based reconstruction (PRIMOR) method, which improves prior-based reconstruction (PBR) by adding a penalty function that includes a model of motion. The prior image is generated as the average of all the respiratory gates, reconstructed with FDK.

Reproducibility of brain-cognition relationships using three cortical surface-based protocols: An exhaustive analysis based on cortical thickness.

People differ in their cognitive functioning. This variability has been exhaustively examined at the behavioral, neural and genetic level to uncover the mechanisms by which some individuals are more cognitively efficient than others. Studies investigating the neural underpinnings of interindividual differences in cognition aim to establish a reliable nexus between functional/structural properties of a given brain network and higher order cognitive performance.

Comparison of total variation with a motion estimation based compressed sensing approach for self-gated cardiac cine MRI in small animal studies.

Purpose: Compressed sensing (CS) has been widely applied to prospective cardiac cine MRI. The aim of this work is to study the benefits obtained by including motion estimation in the CS framework for small-animal retrospective cardiac cine.

Methods: We propose a novel B-spline-based compressed sensing method (SPLICS) that includes motion estimation and generalizes previous spatiotemporal total variation (ST-TV) methods by taking into account motion between frames.