Brain-Computer Interfaces Using Flexible Electronics: An a-IGZO Front-End for Active ECoG Electrodes.

Brain-computer interfaces (BCIs) are evolving toward higher electrode count and fully implantable solutions, which require extremely low power densities (<15mW cm). To achieve this target, and allow for a large and scalable number of channels, flexible electronics can be used as a multiplexing interface. This work introduces an active analog front-end fabricated with amorphous Indium-Gallium-Zinx-Oxide (a-IGZO) Thin-Film Transistors (TFTs) on foil capable of active matrix multiplexing.

An Event-Based Neural Compressive Telemetry With >11× Loss-Less Data Reduction for High-Bandwidth Intracortical Brain Computer Interfaces.

Intracortical brain-computer interfaces offer superior spatial and temporal resolutions, but face challenges as the increasing number of recording channels introduces high amounts of data to be transferred. This requires power-hungry data serialization and telemetry, leading to potential tissue damage risks. To address this challenge, this paper introduces an event-based neural compressive telemetry (NCT) consisting of 8 channel-rotating Δ-ADCs, an event-driven serializer supporting a proposed ternary address event representation protocol, and an event-based LVDS driver.

A Single-Molecule Bioelectronic Portable Array for Early Diagnosis of Pancreatic Cancer Precursors.

A cohort of 47 patients is screened for pancreatic cancer precursors with a portable 96-well bioelectronic sensing-array for single-molecule assay in cysts fluid and blood plasma, deployable at point-of-care (POC). Pancreatic cancer precursors are mucinous cysts diagnosed with a sensitivity of at most 80% by state-of-the-art cytopathological molecular analyses (e.g.

Comparison and Integration of Voltage and Charge Amplifiers for Capacitive ECG Measurements.

Objective: Sensing with capacitive electrodes is of interest for long-term, comfortable bio-potential measurements (e.g., ECG).

A Prototype System With Custom-Designed RX ICs for Contrast-Enhanced Ultrasound Imaging.

This work presents a prototype system based on a multichannel receiving (RX) integrated circuit (IC) for contrast-enhanced ultrasound (CEUS) imaging. The RX IC is implemented in a 40-nm low-voltage CMOS technology and is designed to interface to a capacitive micromachined ultrasonic transducer array. To enable a direct connection of the RX electronics to the transducer, an analog multiplexer with on-chip protection circuitry is developed.

An RX AFE With Programmable BP Filter and Digitization for Ultrasound Harmonic Imaging.

This paper presents a front-end integrated circuit for ultrasound (US) harmonic imaging, interfacing to a one-dimensional capacitive micromachined ultrasonic transducer (CMUT). It contains a complete ultrasound receiving chain, from analog front-end (AFE) to gigabit/s data link. A two-stage self-biased inverter-based transimpedance amplifier (TIA) is proposed in this work to improve tradeoffs between power, noise, and linearity at the first stage.

Ultra-high gain diffusion-driven organic transistor.

Emerging large-area technologies based on organic transistors are enabling the fabrication of low-cost flexible circuits, smart sensors and biomedical devices. High-gain transistors are essential for the development of large-scale circuit integration, high-sensitivity sensors and signal amplification in sensing systems. Unfortunately, organic field-effect transistors show limited gain, usually of the order of tens, because of the large contact resistance and channel-length modulation.

Ambipolar Organic Tri-Gate Transistor for Low-Power Complementary Electronics.

Ambipolar transistors typically suffer from large off-current inherently due to ambipolar conduction. Using a tri-gate transistor it is shown that it is possible to electrostatically switch ambipolar polymer transistors from ambipolar to unipolar mode. In unipolar mode, symmetric characteristics with an on/off current ratio of larger than 10(5) are obtained.

A Low-Voltage Chopper-Stabilized Amplifier for Fetal ECG Monitoring With a 1.41 Power Efficiency Factor.

This paper presents a low-voltage current-reuse chopper-stabilized frontend amplifier for fetal ECG monitoring. The proposed amplifier allows for individual tuning of the noise in each measurement channel, minimizing the total power consumption while satisfying all application requirements. The low-voltage current reuse topology exploits power optimization in both the current and the voltage domain, exploiting multiple supply voltages (0.

A 155 μ W 88-dB DR discrete-time ∆Σ modulator for digital hearing aids exploiting a summing SAR ADC quantizer.

This paper presents a low-power switched-capacitor ∆Σ modulator for digital hearing-aid applications that features a novel summing successive approximation (SAR). The summing SAR performs multi-bit quantization together with the analog addition required in feed-forward (FF) ∆Σ modulator (∆ΣM) topologies, with no attenuation of the input signals and no need for amplifiers. The prototype is implemented in a 0.

Ordered semiconducting self-assembled monolayers on polymeric surfaces utilized in organic integrated circuits.

We report on a two-dimensional highly ordered self-assembled monolayer (SAM) directly grown on a bare polymer surface. Semiconducting SAMs are utilized in field-effect transistors and combined into integrated circuits as 4-bit code generators. The driving force to form highly ordered SAMs is packing of the liquid crystalline molecules caused by the interactions between the linear alkane moieties and the pi-pi stacking of the conjugated thiophene units.

Flexible active-matrix displays and shift registers based on solution-processed organic transistors.

At present, flexible displays are an important focus of research. Further development of large, flexible displays requires a cost-effective manufacturing process for the active-matrix backplane, which contains one transistor per pixel. One way to further reduce costs is to integrate (part of) the display drive circuitry, such as row shift registers, directly on the display substrate.