Cognition in Friedreich's ataxia: a behavioral and multimodal imaging study.

Objective: Friedreich's ataxia (FRDA) is a spinocerebellar degenerative disorder, in which cognitive deficits are sparsely explored. In this behavioral and multimodal magnetic resonance imaging (MRI) study, we investigated the neurocognitive profile and cortico-cerebellar dysfunctions underlying executive functioning in individuals with FRDA.

Methods: 22 FRDA patients and 22 controls were clinically and neuropsychologically examined.