Microsporidia are obligate intracellular parasites related to fungi that cause severe infections in immunocompromised individuals. is a microsporidian species capable of infecting mammals, including human and rodents. In response to microsporidian infection, innate immune system serves as the first line of defense and allows a partial clearance of the parasite via the innate immune cells, namely macrophages, neutrophils, dendritic cells, and Natural Killer cells.
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