[Endobronchial changes in sarcoidosis].

The first case of endobronchial sarcoidosis was described by Benedict and Castelman in 1941. The endoscopic aspects in sarcoidosis can reveal: erythema, edema, network of capillary ectases, granularity, irregular mucosa thickening, macro and micro nodules in mucosa, bronchial and tracheal stenosis, distortions, tractions (including at the large and medium airways), sometimes bronchial ectases secondary to these modifications. The doctors must be aware of the possibility of affecting the great airways in sarcoidosis, such situation, although rare, could make for a difficult diagnosis, especially in the case of the tusigen syndrome or persistent and unexplained wheezing.

[Natural course of preneoplastic bronchial lesions].

Advances in endoscopic technology have improved the detection of precancerous bronchial lesions associated with the occurence of proximal squamous cell lung cancer (SCC) in high-risk individuals for broncho-pulmonary neoplasm. The debates and controversies regarding the control and treatment of intraepitelial bronchial lesions is due to the fact that the regression rate of all preneoplastic bronchial lesions is 54%. But the progression to carcinoma in situ or to cancer is significantly higher for severe dysplasia, than for preneoplastic lesions showing lower-grade dysplasia, such as squamous metaplasia and mild or moderate dysplasia.

[First experiences of non-invasive positive-pressure ventilation at home in chronic respiratory failure in Romania].

The authors are describing the first two cases of noninvasive positive pressure ventilation at home from our country, applied for chronic respiratory failure, demonstrating the advantages and modalities of approach to tackle this new concept of treatment.