A tale of two systems: perceptions of primary care for depression in London and Melbourne.

Background: Depression represents a major and growing disease burden. About 90% of depressed patients are treated solely in primary care, yet there are system-related barriers to primary care for people with depression in the UK and Australia, countries which have different health care arrangements.

Objectives: The aim was to explore the views of GPs and patients in London and Melbourne about primary care system features which support or hinder best care for mild-to-moderate depression.

Systematic review of the empirical evidence of study publication bias and outcome reporting bias.

Background: The increased use of meta-analysis in systematic reviews of healthcare interventions has highlighted several types of bias that can arise during the completion of a randomised controlled trial. Study publication bias has been recognised as a potential threat to the validity of meta-analysis and can make the readily available evidence unreliable for decision making. Until recently, outcome reporting bias has received less attention.

Factors influencing the publication of health research.

Objectives: Assess the degree to which research project findings were published and explore factors that influenced publication.

Methods: Questionnaire to project leaders. Classification of publications and findings.