Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness.

Blindness arising from retinal or macular degeneration results in significant social, health and economic burden. While approved treatments exist for neovascular (') age-related macular degeneration, new therapeutic targets/interventions are needed for the more prevalent atrophic (') form of age-related macular degeneration. Similarly, in inherited retinal diseases, most patients have no access to an effective treatment.