Publications by authors named "Eugene May"
Article Synopsis
- Patients with AQP4-IgG+ neuromyelitis optica spectrum disorders (NMOSDs) often experience optic neuritis, leading to retinal nerve damage, but the link between this damage and primary astrocytopathy is unclear.
- This study compared retinal layer changes among 197 AQP4-IgG+ patients, 32 MOG-IgG+ patients, and 75 healthy controls using optical coherence tomography (OCT) and found no significant thinning in the outer retinal layers of AQP4-IgG+ patients.
- The research indicates that outer retinal damage may not be a consistent outcome of retinal astrocytic injury in AQP4-IgG+ NMOSD, suggesting the need
Retinal Optical Coherence Tomography in Neuromyelitis Optica.
Neurol Neuroimmunol Neuroinflamm
November 2021
Background And Objectives: To determine optic nerve and retinal damage in aquaporin-4 antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a large international cohort after previous studies have been limited by small and heterogeneous cohorts.
Methods: The cross-sectional Collaborative Retrospective Study on retinal optical coherence tomography (OCT) in neuromyelitis optica collected retrospective data from 22 centers. Of 653 screened participants, we included 283 AQP4-IgG-seropositive patients with NMOSD and 72 healthy controls (HCs).
Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders (CROCTINO).
BMJ Open
October 2020
Purpose: Optical coherence tomography (OCT) captures retinal damage in neuromyelitis optica spectrum disorders (NMOSD). Previous studies investigating OCT in NMOSD have been limited by the rareness and heterogeneity of the disease. The goal of this study was to establish an image repository platform, which will facilitate neuroimaging studies in NMOSD.
View Article and Find Full Text PDFOver the past decade, neurology advocacy has caught the attention of neurologists feeling increasingly frustrated about the health care environment in which they practice. We describe our experience in practicing advocacy at the national and local levels. Neurologists can participate in many levels of advocacy to benefit their patients and their profession.
View Article and Find Full Text PDFPurpose: To delineate the disease course and prognosis of patients with mass lesions of the fourth nerve presumed to be schwannomas.
Design: Nonrandomized retrospective case series.
Participants: Thirty-seven consecutive cases of presumed trochlear nerve schwannoma from 9 tertiary university neuro-ophthalmology centers.
Objective: To report the occurrence of life-threatening polyneuropathy in association with renal cell carcinoma.
Methods: Case report and review of the medical literature.
Results: A 65-year-old man developed a fulminant, life-threatening sensory motor polyneuropathy several months before renal cell carcinoma was identified.