Sensitivity study of prompt gamma imaging of scanned beam proton therapy in heterogeneous anatomies.

Background And Purpose: To investigate the use of a fast analytical prediction algorithm in the evaluation of the accuracy in Bragg peak position estimation using prompt gamma imaging in realistic anatomies.

Material And Methods: Brain, nasal cavity and lung spot scanning treatments were planned on an anthropomorphic phantom. Plan delivery in a clinical proton therapy facility was monitored using a prompt gamma camera.