Publications by authors named "Eto F"

Background: Synthetic magnetic resonance imaging (MRI) is an innovative MRI technology that enables the acquisition of multiple quantitative values, including T1 and T2 values, proton density, and myelin volume, in a single scan. Although the usefulness of myelin measurement with synthetic MRI has been reported for assessing several diseases, investigations in patients with stroke have not been reported. We aimed to explore the utility of myelin quantification using synthetic MRI in predicting outcomes in patients with acute ischemic stroke.

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  • * Out of 451 patients over 65 years with cervical fractures, 69% had mid-cervical injuries while 31% had lower-cervical injuries, with lower-cervical injuries being linked to more high-energy trauma cases.
  • * Although lower-cervical injuries resulted in fewer muscle weaknesses compared to mid-cervical injuries, many patients still experienced neurological deficits and similar overall complication rates after treatment, such as respiratory issues but no significant differences in mortality or mobility outcomes.
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Introduction: Preoperative estimations of blood loss are important when planning surgery for cervical spine injuries in older adults. The association between ankylosis and blood loss in perioperative management is of particular interest. This multicenter database review aimed to evaluate the impact of ankylosis on surgical blood loss volume in elderly patients with cervical spine injury.

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Objectives: Periodontal disease is reportedly associated with an increased risk of stroke. Recent evidence suggests that periodontal disease aggravates cerebral small vessel disease (CSVD), including lacunar stroke. However, the periodontal pathogens associated with CSVD remain unclear.

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  • This study analyzed 389 patients aged 65 and older with cervical spinal cord injury (CSCI) but no bone injury to assess the effects of diabetes on neurological recovery.
  • The research found that there were no significant differences in neurological outcomes between diabetic patients and those without diabetes at 6 months post-injury.
  • Additionally, moderate-severe diabetes did not adversely impact recovery, suggesting that diabetic patients had similar improvements in neurological function as their nondiabetic counterparts.
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Objective: To evaluate the pregabalins adjuvant effect in patients with carpal tunnel syndrome (CTS) surgically treated, analyzing postoperative pain and the incidence of complex regional pain syndrome (CRPS).

Methods: Outpatient surgical candidates with CTS were selected and followed for 12 months, divided into three groups. The Control Group received a placebo, the Pregabalin 75 mg Group received a daily dose, and the Pregabalin 150 mg Group received a daily dose of the medication.

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  • Dysphagia, a serious swallowing disorder, affects older adults post-spinal cord injury, particularly those with cervical injuries, though its risk factors are not well understood.
  • A study involving 707 patients aged 65 and older identified male sex, low nutritional status (GNRI <92), dementia, fractures, complete paralysis, anterior surgery, and tracheostomy as significant risk factors for dysphagia.
  • The findings suggest that a low geriatric nutritional risk index (GNRI) is a key indicator of dysphagia risk, implying that nutritional health is critical for recovery in elderly patients with cervical spinal injuries.
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  • * Participants were divided into three groups: one received a placebo, another received 75mg of pregabalin daily, and the third received 150mg daily, with their pain and progress monitored over 12 months.
  • * Results indicated that pregabalin did not significantly improve pain relief or reduce the incidence of CRPS in CTS surgical patients, suggesting it may not be a helpful addition to their treatment plan.
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A 48-year-old man with no history of diagnosis with any abnormality was admitted to our hospital 43 min after onset of stroke. He had a right conjugate deviation and severe left hemiparesis, and his initial National Institutes of Health Stroke Scale (NIHSS) score was 13. Computed tomography (CT) of the head revealed no early ischemic changes, while CT angiography showed occlusion of the M1 proximal segment of the right middle cerebral artery.

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Purpose: The cross-sectional area (CSA) of the cervical vagus nerve (VN), as assessed through ultrasonography, might be linked to autonomic nervous system dysfunction. Hypertension is the primary factor associated with cerebral white matter lesions (WMLs), but there is also evidence of a connection with autonomic nervous system dysfunction. However, the associations between WMLs and VN size are unclear.

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Introduction: Oral care is crucial for the prevention of cardiovascular events and pneumonia. However, few studies have evaluated the associations between multidimensional assessments of oral status or functional outcomes and hospital-acquired pneumonia (HAP).

Methods: Consecutive patients with acute ischemic stroke (AIS) were retrospectively analyzed.

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  • Obesity and rapid weight gain are linked to severe disease from COVID-19, with societal changes during the pandemic affecting health behaviors like nutrition and exercise, contributing to weight gain.
  • A study analyzed healthcare records of over 17 million adults in England to assess weight gain before and during the pandemic, classifying individuals based on their rates of weight change and identifying those with significant increases.
  • Using logistic regression, researchers examined various factors (age, sex, deprivation level, ethnicity) associated with rapid weight gain and the acceleration of weight gain during COVID-19.
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  • An 11-year-old boy developed a cardioembolic stroke after being treated for Ewing sarcoma with high-dose chemotherapy, including doxorubicin.
  • He presented with severe aphasia and imaging revealed a blockage in the left middle cerebral artery, along with significant heart dysfunction and a thrombus.
  • After receiving intravenous thrombolysis, the blockage was successfully cleared, and the patient showed no neurological deficits upon discharge, indicating potential for reperfusion therapy in similar pediatric cases.
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  • This study examined how malnutrition affects older patients (65+) with cervical spinal cord injuries and their outcomes after treatment.
  • Among 789 patients, 6% had major nutritional risks at the start, which impacted their survival and recovery.
  • Results showed that those with major nutritional risks had a significantly higher death rate, shorter lifespan, less neurological improvement, and greater difficulty with daily activities a year after their injury compared to matched controls.
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Multimorbidity, the presence of a chronic condition in addition to cancer, is of particular importance to cancer survivors. It has an impact on the progression, stage at diagnosis, prognosis, and treatment of cancer patients. Evidence is scarce on the prevalence of specific comorbidities in survivors of different cancers to inform prevention and management of multimorbidity.

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Purpose: This study examined the determinants of mobile health (M-Health) application, adoption, usage and discontinuation among corporate workers diagnosed with hypertension and diabetes in Ghana.

Design/methodology/approach: The diffusion innovation and reasoned action theories were employed using an exploratory design. Three hundred corporate workers diagnosed with diabetes and hypertension from three health facilities for the past six months were sampled for the study using a multi-stage sampling technique and administered questionnaires.

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  • The study investigated the prognosis and factors predicting neurological improvement in older patients (65+) with incomplete spinal cord injuries classified as AIS-C.
  • Significant differences in age, body mass index, pre-traumatic activities of daily living, and serum albumin concentrations were found among groups based on their final neurological status.
  • Approximately 64.2% of patients improved to AIS-D, with only 7.1% achieving AIS-E, indicating that while many showed some improvement, complete recovery was rare and linked to higher serum albumin levels and independent pre-injury ADL.
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Background: COVID-19 pandemic restrictions may have influenced behaviours related to weight.

Aim: To describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic.

Design And Setting: An observational cohort study using the routinely collected health data of approximately 40% of adults living in England, accessed through the OpenSAFELY service inside TPP.

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Study Design: Retrospective multicenter study.

Objectives: The effectiveness of early surgery for cervical spinal injury (CSI) has been demonstrated. However, whether early surgery improves outcomes in the elderly remains unclear.

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Introduction: The fibrosis-4 (FIB-4) index and the fibrosis-5 (FIB-5) index are noninvasive markers of liver fibrosis in patients with nonalcoholic fatty liver disease. Although liver fibrosis a potential risk factor for stroke development, it is uncertain whether liver fibrosis influences stroke outcomes. We investigated the associations between these two indices and stroke patient outcomes and compared their predictive accuracy.

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Background: The population prevalence of multimorbidity (the existence of at least 2 or more long-term conditions [LTCs] in an individual) is increasing among young adults, particularly in minority ethnic groups and individuals living in socioeconomically deprived areas. In this study, we applied a data-driven approach to identify clusters of individuals who had an early onset multimorbidity in an ethnically and socioeconomically diverse population. We identified associations between clusters and a range of health outcomes.

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Introduction: Lumbar spondylolysis is a common fatigue fracture of the pars interarticularis of the lamina of the lumbar spine in adolescent athletes presenting with pars clefts. Some pseudarthrotic lumbar spondylolysis causes low back pain or radiculopathy. This study presents a case of pseudarthrotic lumbar spondylolysis that was successfully treated using a modified smiley face rod technique.

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  • Brain function depends on quick electrical communication between neurons and synchrony of neural activity, with myelin sheaths playing a crucial role in this process.
  • The study explored how myelin lipid composition changes during different stages of motor learning in mice, finding that sphingomyelin increases early on, while galactosylceramide levels rise later on.
  • Inhibiting galactosylceramide synthesis related to myelin affects motor learning, indicating that adjustments in myelin lipid composition are important for effective learning processes.
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