Publications by authors named "Etienne Bizot"
Regarding nirsevimab immunization status, among 1085 infants hospitalized for bronchiolitis, the odds of hospitalization for respiratory syncytial virus bronchiolitis were 4.7 times higher for nonimmunized children. Immunized infants were less likely to require oxygen supplementation (20.
View Article and Find Full Text PDFBackground: Enterococcal bloodstream infections (EBSIs) are rare infections in children associated with 5%-10% of mortality in previous studies. The recent evolution of antimicrobial resistance and therapies require updated data.
Methods: We conducted an observational retrospective study between January 2008 and December 2019 describing the characteristics of children with EBSI in a French pediatric hospital.
We described and characterized Shiga-toxin-producing Escherichia coli (STEC) strains with high levels of resistance to azithromycin isolated in France between 2004 and 2020. Nine of 1,715 (0.52%) STEC strains were resistant to azithromycin, with an increase since 2017.
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- O80:H2 enterohemorrhagic (EHEC) strain ST301 is a key culprit in causing hemolytic uremic syndrome in Europe, with potential for invasive infections due to extra-intestinal virulence factors.
- Researchers identified a new clone in France related to ST301 by using SNP-phylogeny analysis to compare various strains and their traits, including virulence and antibiotic resistance.
- The study found that there are two main groups within ST301: one primarily containing enteropathogenic strains and another mostly comprising EHEC strains, highlighting the need for ongoing monitoring of these virulent clones, particularly the O55:H9 strain in Europe.
Enterohemorrhagic Escherichia coli (EHEC) O80:H2, belonging to sequence type ST301, is among the main causes of hemolytic and uremic syndrome in Europe, a major concern in young children. Aside from the usual intimin and Shiga toxin virulence factors (VFs), this emerging serotype possesses a mosaic plasmid combining extra-intestinal VF- and antibiotic resistance-encoding genes. This hybrid pathotype can be involved in invasive infections, a rare occurrence in EHEC infections.
View Article and Find Full Text PDFHuman rhinoviruses (HRVs) are the leading cause of common colds. With the development of new molecular methods since the 2000s, HRVs have been increasingly involved among severe clinical infections. Recent knowledge of the HRV genetic characteristics has also improved the understanding of their pathogenesis.
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