Publications by authors named "Ethan Weeks"
Article Synopsis
- - Antibodies are generated by naive B cells turning into plasma cells in germinal centers (GCs) of lymphoid tissues, and patients with B cell lymphoma undergoing immunotherapy have reduced antibody production, leading to higher infection rates and weaker vaccine responses.
- - Current research models struggle to effectively mimic long-term GC functions and assess B cell responses, prompting the development of synthetic hydrogels that replicate the lymphoid tissue environment to support human GCs from various blood sources.
- - The new immune organoid systems maintain critical B cell functions longer and offer unique immune programming features; however, they show less effectiveness with lymphoma-derived B cells, indicating a rapid method for studying immune responses and B cell-related disorders.
