LanTERN: A Fluorescent Sensor That Specifically Responds to Lanthanides.

Lanthanides, a series of 15 f-block elements, are crucial in modern technology, and their purification by conventional chemical means comes at a significant environmental cost. Synthetic biology offers promising solutions. However, progress in developing synthetic biology approaches is bottlenecked because it is challenging to measure lanthanide binding with current biochemical tools.

Synthetic microbiology in sustainability applications.

Microorganisms are a promising means to address many societal sustainability challenges owing to their ability to thrive in diverse environments and interface with the microscale chemical world via diverse metabolic capacities. Synthetic biology can engineer microorganisms by rewiring their regulatory networks or introducing new functionalities, enhancing their utility for target applications. In this Review, we provide a broad, high-level overview of various research efforts addressing sustainability challenges through synthetic biology, emphasizing foundational microbiological research questions that can accelerate the development of these efforts.

Diagnosis of Posterior and Combined-Type Shoulder Instability: A 10-Year Cross-sectional Study From a Single Military Base.

Background: Large variations exist in the reported frequency and etiology of posterior and combined shoulder instability in the active-duty military population.

Purpose: To compare imaging and clinical examination findings as well as reoperation rates between active-duty military patients who underwent surgery for anterior, posterior, and combined-type shoulder instability.

Study Design: Cross-sectional study; Level of evidence, 3.

Opioid Use and Associated Patient Satisfaction With Pain Control After Endoscopic Surgery and Robotic-Assisted Radical Prostatectomy.

Objective: To evaluate patient reported measures in patients undergoing endourologic procedures and robotic assisted radical prostatectomy (RARP) to demonstrate the efficacy of non-opioid postoperative pain management strategies.

Materials And Methods: A prospective cohort study performed at an academic medical center included a patient telephone questionnaire and chart review. Opioid prescriptions, opioid use, and patient reported outcomes were recorded.

Patient Factors Associated with High Opioid Consumption after Common Surgical Procedures Following State-Mandated Opioid Prescription Regulations.

Background: State regulations have decreased prescribed opioids with more than 25% of patients abstaining from opioids. Despite this, 2 distinct populations of patients exist who consume "high" or "low" amounts of opioids. The aim of this study was to identify factors associated with postoperative opioid use after common surgical procedures and develop an opioid risk score.

"Every time the phone rings, my heart stops": Mothers' emotional responses to having a young adult child with a substance use disorder.

When a young adult develops a substance use disorder (SUD), a parent often assumes a caregiving role, and experiences burdens associated with this off-time life event (Kaur et al., 2018). Mothers and children reciprocally influence one another's emotional processes, impacting proximal process (Bronfenbrenner & Evans, 2000; Bronfenbrenner & Morris, 1998).

A harmonised, high-coverage, open dataset of solar photovoltaic installations in the UK.

Solar photovoltaic (PV) is an increasingly significant fraction of electricity generation. Efficient management, and innovations such as short-term forecasting and machine vision, demand high-resolution geographic datasets of PV installations. However, official and public sources have notable deficiencies: spatial imprecision, gaps in coverage and lack of crucial meta data, especially for small-scale solar panel installations.

Patients' Experience With Opioid Pain Medication After Discharge From Surgery: A Mixed-Methods Study.

Background: Decreasing the number of prescription opioids has been a leading strategy in combating the opioid epidemic. In Vermont, statewide and institutional policies have affected prescribing practices, resulting in a 40% decrease in postoperative opioid prescribing. The optimal approach to postoperative opioid prescribing remains unknown.

The genetic insulator RiboJ increases expression of insulated genes.

A primary objective of synthetic biology is the construction of genetic circuits with behaviors that can be predicted based on the properties of the constituent genetic parts from which they are built. However a significant issue in the construction of synthetic genetic circuits is a phenomenon known as context dependence in which the behavior of a given part changes depending on the choice of adjacent or nearby parts. Interactions between parts compromise the modularity of the circuit, impeding the implementation of predictable genetic constructs.