Atorvastatin efficiency after traumatic brain injury in rats.

Background: The neuroprotective effects of statins possibly depend on their pleiotropic effect such as antioxidative and anti-inflammatory properties. In this study, we have evaluated the efficiency of atorvastatin on brain edema, lipid peroxidation, and ultrastructural changes in TBI animal model.

Methods: Modified Feeney method has been used for the trauma model in rats.