Bipolar Supercapacitive Performance of N-Containing Carbon Materials Derived from Covalent Triazine-Based Framework.

The search for new electrode materials for bipolar-supercapacitor performance is the intention of numerous research in the area of functional framework materials. Among various electrode materials, covalent triazine-based frameworks (CTFs) are in the spotlight drawing much attention as potential electrode material for energy storage owing to their tunable surface area, pore size distribution, and heteroatom content. Herein, we present the synthesis of nitrogen-functionalized CTFs marked as CTF-Py-600 and CTF-Py-700 with high nitrogen content (18 % and 14 %, respectively) for supercapacitor application by applying the 2,6-dicyanopyridine monomer via the polymerization reaction under ionothermal condition.

Highly electrochemically active TiCTx MXene/MWCNT nanocomposite for the simultaneous sensing of paracetamol, theophylline, and caffeine in human blood samples.

The facile fabrication is reported of highly electrochemically active TiCTx MXene/MWCNT (3D/1D)-modified screen-printed carbon electrode (SPE) for the efficient simultaneous electrochemical detection of paracetamol, theophylline, and caffeine in human blood samples. 3D/1D TiCTx MXene/MWCNT nanocomposite was synthesized using microwave irradiation and ultrasonication processes. Then, the TiCTx/MWCNT-modified SPE electrode was fabricated and thoroughly characterized towards its physicochemical and electrochemical properties using XPS, TEM, FESEM, XRD, electrochemical impedance spectroscopy, cyclic voltammetry, and differential pulse voltammetry techniques.

Assessment of seed- and seedling-related traits in (Indian sandalwood) reveals high adaptive potential.

Seed and seedling traits govern plant fitness and persistence and are influenced by the interaction between the plant and its environment. Changing climatic and edaphic conditions will drastically affect early fitnessrelated traits and can alter the demography and species distribution range. It is widely documented that trait variation among populations may increase resilience of tree communities and reduce the risk of extinction under future climates.

Layer-by-Layer Assembly of CTAB-rGO-Modified MXene Hybrid Films as Multifunctional Electrodes for Hydrogen Evolution and Oxygen Evolution Reactions, Supercapacitors, and DMFC Applications.

Exceptional electrical conductivity and abundance of surface terminations like-F- and OH- leading to hydrophilicity make the family of 2D transition metal carbides/nitrides and carbonitrides (MXene) excellent candidates for energy storage and conversion applications. MXenes, however, undergo restacking of nanosheets via van der Waals interaction, hindering the active sites, leading to slow electronic and ionic kinetics, and ultimately affecting their electrochemical performance. Herein, we report binder-free cetyltrimethylammonium bromide-reduced graphene oxide (CTAB-rGO)-modified MXene hybrid films on nickel foam as a promising noble metal-free multifunctional electrode synthesized via layer-by-layer assembly and dip coating techniques, which effectively reduce restacking while improving the kinetics.

Effect of Microwave Irradiation on the Dielectric Characteristics of Semi-Conductive Nanoparticle-Based Nanofluids: Progress towards the Microwave Synthesis.

Studies on dispersing nanoparticles in base fluid to elevate its essential and critical properties have evolved significantly in the recent decade. Alongside the conventional dispersion techniques used for nanofluid synthesis, microwave energy at 2.4 GHz frequency is irradiated onto the nanofluids is experimented with in this study.

Eco-friendly fabrication of nonenzymatic electrochemical sensor based on cobalt/polymelamine/nitrogen-doped graphitic-porous carbon nanohybrid material for glucose monitoring in human blood.

The design and development of eco-friendly fabrication of cost-effective electrochemical nonenzymatic biosensors with enhanced sensitivity and selectivity are one of the emerging area in nanomaterial and analytical chemistry. In this aspect, we developed a facile fabrication of tertiary nanocomposite material based on cobalt and polymelamine/nitrogen-doped graphitic porous carbon nanohybrid composite (Co-PM-NDGPC/SPE) for the application as a nonenzymatic electrochemical sensor to quantify glucose in human blood samples. Co-PM-NDGPC/SPE nanocomposite electrode fabrication was achieved using a single-step electrodeposition method under cyclic voltammetry (CV) technique under 1 M NHCl solution at 20 constitutive CV cycles (sweep rate 20 mV/s).

Pantoprazole associated dyspepsia hypocalcemia and hyponatremia: A disproportionality analysis in FDA adverse event reporting system (FAERS) database.

Background And Study Aim: The study was designed to detect novel Adverse Events (AEs) of pantoprazole by disproportionality analysis in the FDA (Food and Drug Administration) database of Adverse Event Reporting System (FAERS) using Data Mining Algorithms (DMAs). Pantoprazole, the most commonly over-utilized Over The Counter (OTC) medication, was selected to assess any short-term or long-term AEs. The study aimed to analyze the novel adverse events of pantoprazole using the FAERS database.

Exploring the Superior Anchoring Performance of the Two-Dimensional Nanosheets BCP and BCP for Lithium-Sulfur Batteries.

Potential anchoring materials in lithium-sulfur batteries help overcome the shuttle effect and achieve long-term cycling stability and high-rate efficiency. The present study investigates the two-dimensional nanosheets BCP and BCP by employing density functional theory calculations for their promise as anchoring materials. The nanosheets BCP and BCP bind polysulfides with adsorption energies in the range from -2.

A Road Map toward Field-Effect Transistor Biosensor Technology for Early Stage Cancer Detection.

Field effect transistor (FET)-based nanoelectronic biosensor devices provide a viable route for specific and sensitive detection of cancer biomarkers, which can be used for early stage cancer detection, monitoring the progress of the disease, and evaluating the effectiveness of therapies. On the road to implementation of FET-based devices in cancer diagnostics, several key issues need to be addressed: sensitivity, selectivity, operational conditions, anti-interference, reusability, reproducibility, disposability, large-scale production, and economic viability. To address these well-known issues, significant research efforts have been made recently.

Evaluation of Clove Phytochemicals as Potential Antiviral Drug Candidates Targeting SARS-CoV-2 Main Protease: Computational Docking, Molecular Dynamics Simulation, and Pharmacokinetic Profiling.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can cause a sudden respiratory disease spreading with a high mortality rate arising with unknown mechanisms. Still, there is no proper treatment available to overcome the disease, which urges the research community and pharmaceutical industries to screen a novel therapeutic intervention to combat the current pandemic. This current study exploits the natural phytochemicals obtained from clove, a traditional natural therapeutic that comprises important bioactive compounds used for targeting the main protease of SARS-CoV-2.

Efficient and stable perovskite-silicon tandem solar cells through contact displacement by MgF.

The performance of perovskite solar cells with inverted polarity (p-i-n) is still limited by recombination at their electron extraction interface, which also lowers the power conversion efficiency (PCE) of p-i-n perovskite-silicon tandem solar cells. A MgF interlayer with thickness of ~1 nanometer at the perovskite/C interface favorably adjusts the surface energy of the perovskite layer through thermal evaporation, which facilitates efficient electron extraction and displaces C from the perovskite surface to mitigate nonradiative recombination. These effects enable a champion open-circuit voltage of 1.

Awareness and Attitude toward the Replacement of Missing Teeth among Patients at a Dental Institute: A Cross-sectional Study.

Aim: To evaluate the awareness among the patients visiting a dental college in replacing the missing teeth.

Materials And Methods: A cross-sectional survey was conducted to know the patient's awareness and preference for the treatment options. A list of the closed-ended questionnaire was used to record the patient's response about being edentulous.

VS wrapped Si nanowires as core-shell heterostructure photocathode for highly efficient photoelectrochemical water reduction performance.

Interfacing an electrocatalyst with photoactive semiconductor surfaces is an emerging strategy to enhance the photocathode performance for the solar water reduction reaction. Herein, a core-shell heterostructure photocathode consisting of vanadium disulfide (VS) as a 2D layered electrocatalyst directly deposited on silicon nanowire (Si NWs) surface is realized via single-step chemical vapor deposition towards efficient hydrogen evolution under solar irradiation. In an electrochemical study, 2D VS/Si NWs photocathode exhibits a saturated photocurrent density (17 mA cm) with a maximal photoconversion efficiency of 10.

Reporting dinaciclib and theodrenaline as a multitargeted inhibitor against SARS-CoV-2: an study.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is one of the rapid spreading coronaviruses that belongs to the Coronaviridae family. The rapidly evolving nature of SARS-CoV-2 results in a variety of variants with a capability of evasion to existing therapeutics and vaccines. So, there is an imperative need to discover potent drugs that can able to disrupt the function of multiple drug targets to tackle the SARS-CoV-2 menace.

Unusual Activity of Rationally Designed Cobalt Phosphide/Oxide Heterostructure Composite for Hydrogen Production in Alkaline Medium.

Design and development of an efficient, nonprecious catalyst with structural features and functionality necessary for driving the hydrogen evolution reaction (HER) in an alkaline medium remain a formidable challenge. At the root of the functional limitation is the inability to tune the active catalytic sites while overcoming the poor reaction kinetics observed under basic conditions. Herein, we report a facile approach to enable the selective design of an electrochemically efficient cobalt phosphide oxide composite catalyst on carbon cloth (CoP-CoO/CC), with good activity and durability toward HER in alkaline medium (η = -43 mV).

Damp heat-stable perovskite solar cells with tailored-dimensionality 2D/3D heterojunctions.

If perovskite solar cells (PSCs) with high power conversion efficiencies (PCEs) are to be commercialized, they must achieve long-term stability, which is usually assessed with accelerated degradation tests. One of the persistent obstacles for PSCs has been successfully passing the damp-heat test (85°C and 85% relative humidity), which is the standard for verifying the stability of commercial photovoltaic (PV) modules. We fabricated damp heat-stable PSCs by tailoring the dimensional fragments of two-dimensional perovskite layers formed at room temperature with oleylammonium iodide molecules; these layers passivate the perovskite surface at the electron-selective contact.

Predictive modeling and therapeutic repurposing of natural compounds against the receptor-binding domain of SARS-CoV-2.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the Coronaviridae family, causing major destructions to human life directly and indirectly to the economic crisis around the world. Although there is significant reporting on the whole genome sequences and updated data for the different receptors are widely analyzed and screened to find a proper medication. Only a few bioassay experiments were completed against SARS-CoV-2 spike protein.

Cytogenetic Consequences of Food Industry Workers Occupationally Exposed to Cooking Oil Fumes (COFs).

Background: Cooking oil fumes (COFs) with smoking habits is a substantial risk that aggravates genetic modifications. The current study was to estimate the biological markers of genetic toxicity counting Micronucleus changes (MN), Chromosome Aberrations (CA) and DNA modifications among COFs exposures and control subjects inherent from South India.

Materials And Methods: Present analysis comprised 212 COFs with tobacco users and equivalent number of control subjects.

Novel nano-engineered environmental sensor based on polymelamine/graphitic-carbon nitride nanohybrid material for sensitive and simultaneous monitoring of toxic heavy metals.

Heavy metal ions (HMIs) pollution is always a serious issue worldwide. Therefore, monitoring HMIs in environmental water is an important and challenging step to ensure environmental health and human safety. In this study, we spotlight an effortless, single-step in-situ electrochemical polymerization deposition technique to fabricate a novel, low-cost, efficient, nano-engineered poly(melamine)/graphitic-carbon nitride nanonetwork (PM/g-CN) modified screen-printed carbon electrode (SPE) for sensitive, selective, and simultaneous electrochemical monitoring of toxic HMIs in environmental waters.

Revisiting CRISPR/Cas-mediated crop improvement: Special focus on nutrition.

Genome editing (GE) technology has emerged as a multifaceted strategy that instantaneously popularised the mechanism to modify the genetic constitution of an organism. The clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated (Cas) protein-based genome editing (CRISPR/Cas) approach has huge potential for efficacious editing of genomes of numerous organisms. This framework has demonstrated to be more economical in contrast to mega-nucleases, zinc-finger nucleases (ZFNs), and transcription activator-like effector nucleases (TALENs) for its flexibility, versatility, and potency.

Probing the effect of a plus 1bp frameshift mutation in protein-DNA interface of domestication gene, , in wheat.

Transcription factor NAM-B1 has a major role in the process of senescence, which results in higher Fe and Zn concentrations in grains of wild wheat (; Td). The absence of the wild type NAMB1 in (Ta), one of the cardinal crops essential for more than 1/3 of the global population, affects Fe and Zn remobilisation to the maturing grain from the flag leaf resulting in lesser micronutrient bioavailability. The cardinal difference in the NAMB1 gene between the two species is the absence of +1 bp allele in Ta.

Prevalence of osteoarthritis of knee joint among adult population in a rural area of Kanchipuram District, Tamil Nadu.

Background: Osteoarthritis (OA) is one of the most common degenerative disorders among the elderly population; although aging is the most important cause, research has shown that it is a complex disease with many etiologies. It is not an inevitable part of aging but rather the result of a combination of factors, many of which can be modified or prevented.

Objective: The objective of this study was to assess the burden and determinants of OA knee among the adult population.

Clinical evaluation of direct composite restoration done for midline diastema closure - long-term study.

Purpose Of The Study: The aim of this study was to evaluate clinically the performance of composite resin used to restore midline diastema between the maxillary and mandibular central incisors.

Methodology: Direct composite restorations were done for 45 patients with midline diastema between the maxillary and mandibular central incisors. Standard protocols were followed for the placement of composite resin for the diastema closure, and recall visits were made for every 6 months for a period of 60 months for evaluation of the success of these restorations made.