Publications by authors named "Estrella Martinez Baringo"

Background: The role of duration of untreated psychosis (DUP) as an early detection and intervention target to improve outcomes for individuals with first-episode psychosis is unknown.

Study Design: PRISMA/MOOSE-compliant systematic review to identify studies until February 1, 2023, with an intervention and a control group, reporting DUP in both groups. Random effects meta-analysis to evaluate (1) differences in DUP in early detection/intervention services vs the control group, (2) the efficacy of early detection strategies regarding eight real-world outcomes at baseline (service entry), and (3) the efficacy of early intervention strategies on ten real-world outcomes at follow-up.

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Article Synopsis
  • Duration of untreated psychosis (DUP) is linked to worse mental health outcomes, and this study conducted a meta-analysis to determine its average duration globally.
  • The findings showed a mean DUP of 42.6 weeks, with significant variations by continent and income levels, with Africa having the longest duration at 70.0 weeks.
  • The research highlights the importance of timely diagnosis and intervention for first episode psychosis, especially in developing countries, to improve mental health outcomes.
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