[Vitamin B12 deficiency associated with high doses od metformin in older people diabetic].

Introduction: The aim of the study was to estimate if B12 deficiency is associated with the use of metformin in the elderly diabetics.

Methods: Case-control study in diabetic OP. Cases (n = 137) were defined as elderly with B12 < 221 pmol/L and controls (n = 279) elderly with B12 > 221 pmol/L.