Publications by authors named "Estrada P"
Backgrounds: Breech presentation, family history, and physical examination are the most recognized risk factors for DDH, which form the basis of selective screening. However, this approach can lead to late diagnosis, invasive treatments, and complications. This study analyzes the effectiveness of selective screening and identifies additional factors related to DDH.
View Article and Find Full Text PDFObjective: We aimed to quantify the mortality risk in a large, well-characterized cohort of patients with Sjögren disease (SjD) and to identify independent predictors of mortality in this population.
Methods: We included 314 patients diagnosed with SjD according to the 2002 American-European Consensus Group criteria from a prospective, multicenter SjögrenSER Prospective cohort. Detailed data on systemic manifestations, serological markers, disease activity, and mortality were collected after a median of 9.
Objective: The purpose of this report is to describe the presentation of a patient with a pectoralis major tendon (PMJ) tear.
Clinical Features: A 30-year-old male weightlifter presented to a chiropractor with localized left arm pain that began while bench-pressing. Ecchymosis and swelling were present, but no contour abnormalities were seen.
Article Synopsis
- Arthrobrachus Solier, 1849 is a genus of beetles in the Melyridae family found mainly in southern South America, consisting of twenty known species.
- A new species, named Arthrobrachus crassicornis sp. nov., has been identified through the study of collection materials.
- This new species is specifically described from Argentina and is located within the South American Transition Zone.
Astylus atromaculatus (Blanchard, 1843), the most widely distributed taxon of the genus, is redescribed. The original description is based mainly on the coloration patterns of the elytra. The study of the external morphological characters and genitalia of the type material and from specimens of collections allows the establishment of a new synonymy between A.
View Article and Find Full Text PDFImmunoglobulin G4-related pancreatitis presenting as an obstructive pancreatic mass in a Latino male.
J Family Community Med
October 2024
Article Synopsis
- IgG4-related disease (IgG4-RD) is an autoimmune condition that can affect various organs, but there is limited research on its occurrence in Latino populations.
- The case report discusses a 40-year-old Latino male diagnosed with IgG4-related pancreatitis, presenting symptoms like diarrhea, jaundice, and elevated liver enzymes.
- After undergoing a biopsy which ruled out cancer, the patient received glucocorticoid therapy that improved his symptoms and liver function, with no negative effects from a COVID-19 infection during treatment.
Objetive: To evaluate the frequency and timing of sustained drug-free remission (SDFR) in patients with giant cell arteritis (GCA) and to identify potential predictive factors of this outcome.
Methods: Retrospective review of all patients included in the large Spanish multicentre registry for GCA (ARTESER) with at least two years of follow-up. SDFR was defined as the absence of typical signs, symptoms, or other features of active GCA for ≥12 months after discontinuation of treatment.
Article Synopsis
- Giant cell arteritis (GCA) is a complex disease with various symptoms and severity levels, and the study aimed to evaluate its different clinical subsets to improve treatment strategies and reduce complications.
- The study categorized GCA into three phenotypes: cranial, extracranial, and occult, analyzing their association with severe complications and survival rates over time.
- Results indicated that cranial GCA had more severe ischemic complications and visual disturbances, while the occult subset showed potential for higher mortality, highlighting the need for targeted treatment approaches based on these clinical patterns.
Imaging studies have transformed the diagnosis of large vessel vasculitis (LVV) involvement in giant cell arteritis (GCA). A positron emission tomography/computed tomography (PET/CT) scan with 18-fluorodeoxyglucose (18F-FDG) has emerged as a valuable tool for assessing LVV. We aimed to determine the utility of an 18F-FDG-PET/CT scan in detecting LVV in GCA in the ARTESER registry.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates the rates of sedation reversal during outpatient endoscopy in different settings, focusing on how a triage tool helps direct higher-risk patients to an in-hospital center for better outcomes.
- - Data from over 97,000 procedures at an ambulatory endoscopy center (AEC-DHC) and nearly 23,000 at an in-hospital ambulatory procedure center (APC) were analyzed from April 2013 to September 2019, revealing low rates of sedation reversal (0.017% at AEC-DHC and 0.04% at APC).
- - The study found that patients needing sedation reversal at both centers had varying characteristics, with significant differences in factors like age, ASA classification,
Introduction: To reach the diagnosis of giant cell arteritis (GCA), signs, symptoms, laboratory tests, imaging findings, and occasionally anatomopathological results from temporal artery biopsy are evaluated. This study describes the results of an algorithm analysis based on clinical and ultrasound evaluation of patients with suspected GCA, highlighting its diagnostic utility by contrasting its use in different clinical suspicion scenarios.
Method: Prospective multicenter study evaluating patients referred with suspected GCA through a preferential circuit (fast track), grouping them according to low or high clinical suspicion of GCA.
In rheumatoid arthritis (RA) synovium, ATP, and ADP are released, sparking inflammation. Ectoenzymes CD39 and CD73 metabolize these purine nucleotides, generating anti-inflammatory adenosine. Therefore, dysregulated CD39 and CD73 expression may impact RA development.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to analyze how common visual symptoms are in patients with Giant Cell Arteritis (GCA) and what factors might predict these symptoms.
- - Out of 1,636 patients with GCA, 36.6% experienced visual issues, with anterior ischemic optic neuropathy being the most common complication; older age and jaw claudication were identified as risk factors for visual involvement.
- - Conversely, conditions like polymyalgia rheumatica, fever, longer symptom duration, and higher erythrocyte sedimentation rate were associated with a lower risk of experiencing visual symptoms.
Article Synopsis
- This study aims to evaluate how effective F-FDG PET-CT scans are for detecting large-vessel involvement in patients suspected of having giant cell arteritis (GCA) who have negative results from temporal artery biopsies (TAB).
- Researchers looked at 127 patients and found that F-FDG PET-CT scans were positive in 61 out of 73 patients finally diagnosed with GCA, resulting in a high sensitivity of 83.5% and good specificity of 85.1%.
- The findings suggest that F-FDG PET-CT is a useful diagnostic tool in identifying large-vessel involvement in GCA cases, especially in patients with negative TAB results.
Background: To examine the performance of the new 2022 American College of Rheumatology (ACR)/EULAR classification criteria for giant cell arteritis (GCA) in routine clinical care, compared with the 1990 ACR GCA classification criteria.
Methods: The fulfilment of 2022 ACR/EULAR and 1990 ACR criteria was tested in our real-life cohort of GCA patients with proven vasculitis by temporal artery biopsy or imaging (a necessary pre-requisite to apply the new criteria is the presence of a confirmed diagnosis of medium- or large-vessel vasculitis). The performance of classification criteria was evaluated in all patients with GCA across different subsets of the disease.
Aloe vera ( Miller) gel is a frequently used ingredient in many food pro-ducts, particularly beverages, due to its reported health benefits. Studies have identified acemannan, a polysaccharide rich in mannose units which are partially or fully acetylated, as the primary bioactive compound in Aloe vera gel. The acemannan content and its degree of acetylation (DA) were measured in 15 different commercial beverages containing Aloe vera at varying concentrations (from 30% to 99.
View Article and Find Full Text PDFCD4 T follicular helper (T) cells are key targets for human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) replication and contribute to the virus reservoir under antiretroviral therapy (ART). Here, we describe a novel CD3 CD20 double-positive (DP) lymphocyte subset, resident in secondary lymphoid organs of humans and rhesus macaques (RMs), that appear predominantly after membrane exchange between T and B cells. DP lymphocytes are enriched in cells displaying a T phenotype (CD4 PD1 CXCR5), function (interleukin 21 positive [IL-21]), and gene expression profile.
View Article and Find Full Text PDFBackground And Aim: Tissue source has been shown to exert a significant effect on the magnitude of associations between telomere length and various health outcomes and exposures. The purpose of the present qualitative review and meta-analysis is to describe and investigate the impact of study design and methodological features on the correlation between telomere lengths measured in different tissues from the same healthy individual.
Methods: This meta-analysis included studies published from 1988 to 2022.
Article Synopsis
- - There is a debate about whether Saturn's main rings are old, formed shortly after the planet, or younger, created during the Late Heavy Bombardment.
- - The rings consist mainly of water-ice but have up to 2% non-icy materials caused by micrometeoroid impacts.
- - Cassini's Cosmic Dust Analyzer measured the micrometeoroid flux, finding it mostly from the Kuiper belt, leading to an estimated ring exposure time of less than 100 to 400 million years, supporting the idea that the rings formed relatively recently.
Article Synopsis
- Uniform chromosome abnormalities are frequently seen in early pregnancy loss, with mosaic autosomal trisomy present in about 10% of cases, highlighting the need for further understanding of its clinical implications.
- A study analyzed data from a large PGT-A database in Brazil between 2019 and 2022 to evaluate the prevalence of mosaicism in embryos, including factors related to maternal age, embryo development day, and quality.
- Results showed that most mosaic aneuploidies were linked to the last three chromosomes, with various associations found for different clinical conditions, indicating that maternal age and embryo quality significantly affect mosaicism rates.
Fabricius (1775) describes Anobium lineatum for Brazil, a species recognized as Astylus (Melyridae). The study of the external morphology and genitalia of the type material and collections allows us to establish Astylus subacuminatus (Solier, 1849) as a synonym of Astylus lineatus (Fabricius, 1775). Likewise, the varieties described by Pic (1919) A.
View Article and Find Full Text PDFObjective: To evaluate the impact of prior glucocorticoid (GC) treatment on the diagnostic accuracy of F-FDG PET-CT in giant cell arteritis (GCA).
Methods: Retrospective study of a consecutive cohort of 85 patients with proven GCA who received high-dose GC before PET-CT.
Results: Thirty-nine patients previously treated with methylprednisolone (MP) boluses, of whom 37% were PET-CT (uptakes grade 3 or 2) positive.
Objective: This study aimed to compare cesarean delivery (CD) rates and maternal/neonatal outcomes before and after the 2014 ACOG/SMFM Obstetric Care Consensus for Safe Prevention of Primary CD.
Study Design: This retrospective study compared unscheduled CD rates and outcomes of singleton, cephalic, term pregnancies at a tertiary-care teaching maternity hospital. Births 5 years before (March 2009-February 2014) and after (June 2014-May 2019) release of the consensus were included.
Objective: The search for new glucocorticoid-sparing disease-modifying anti-rheumatic drugs continues to be an unmet need in large vessel vasculitis (LVV). This report aims to assess the effectiveness and safety of leflunomide (LEF) in Takayasu arteritis (TA) and giant cell arteritis (GCA).
Methods: We systematically reviewed the literature, searching for studies evaluating the efficacy of LEF in LVV.
Article Synopsis
- The study aimed to analyze the diagnostic methods for giant cell arteritis (GCA) in clinical practice and the impact of EULAR recommendations on these methods.
- A retrospective analysis included 1,675 GCA patients across 26 hospitals in Spain, finding that temporal artery biopsy (TAB) was initially the most common diagnostic test but usage declined over time.
- Imaging techniques, particularly ultrasound, significantly increased in use from 2013 to 2019, suggesting a shift in preference for non-invasive diagnostic methods influenced by recent guidelines.