Publications by authors named "Estibaliz Arrieta Ortubay"

Article Synopsis
  • The study examined how administering Remdesivir during the acute phase of COVID-19 affects the development of post-COVID symptoms in hospitalized survivors.
  • It involved a case-control format, comparing 216 survivors who received Remdesivir with 216 who didn't, while controlling for age, sex, BMI, and vaccination status.
  • Findings indicated that receiving Remdesivir acted as a protective factor against long-term post-COVID symptoms like fatigue, pain, and memory loss, suggesting its potential benefits for previously hospitalized COVID-19 patients.
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The SARS-CoV-2 VIrus PERsistence (VIPER) study investigated the presence of long-lasting SARS-CoV-2 RNA in plasma, stool, urine, and nasopharyngeal samples in COVID-19 survivors. The presence of SARS-CoV-2 RNA reverse transcription polymerase chain reactions (RT-PCR) were analyzed within plasma, stool, urine, and nasopharyngeal swab samples in COVID-19 survivors with post-COVID symptoms and a comparison group of COVID-19 survivors without post-COVID symptoms matched by age, sex, body mass index and vaccination status. Participants self-reported the presence of any post-COVID symptom (defined as a symptom that started no later than 3 months after the initial infection).

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Background: Cognitive dysfunction is regarded as one of the most severe aftereffects following coronavirus disease 2019 (COVID-19). Eye movements, controlled by several brain areas, such as the dorsolateral prefrontal cortex and frontal-thalamic circuits, provide a potential metric for assessing cortical networks and cognitive status. We aimed to examine the utility of eye movement measurements in identifying cognitive impairments in long COVID patients.

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Article Synopsis
  • Respiratory failure (RF) is a common and serious complication for patients hospitalized due to influenza, with a reported incidence of 24%, varying widely from 5% to 85%.
  • The systematic review analyzed 36 studies to identify risk factors and found higher RF incidences in patients with pneumonia and during the 2009 influenza pandemic.
  • There are inconsistencies in how RF is defined and reported, making it challenging to compare data across studies and with other respiratory viruses.
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Despite the growing number of patients with persistent symptoms after acute SARS-CoV-2 infection, the pathophysiology underlying long-COVID is not yet well characterized, and there is no established therapy. We performed a deep immune profiling in nine patients with persistent symptoms (PSP), before and after a 4-day prednisone course, and five post-COVID-19 patients without persistent symptoms (NSP). PSP showed a perturbed distribution of circulating mononuclear cell populations.

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