Publications by authors named "Esther von der Weth"
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Synopsis of recent research by authors named "Esther von der Weth"
- Esther von der Weth's recent research primarily focuses on the mechanisms of translation termination in eukaryotic cells, specifically how the ABCF ATPase New1 influences this process.
- Her findings highlight that translation termination efficiency is significantly affected by the context of the stop codon and the interaction with specific tRNA isoacceptors in the P site, emphasizing the complex regulation of peptidyl transferase activity.
- Research indicates that release factors eRF1 and eRF3 play crucial roles in recognizing stop codons and releasing polypeptides, and that modulation by additional factors occurs through interactions at the E-site, shedding light on potential therapeutic targets for translation-related defects.
