Publications by authors named "Esther Zelenovskiy"
Article Synopsis
- The amino acid isoleucine plays a significant role in metabolic health, with lower dietary levels linked to improved health in mice on a Western Diet.
- The effects of isoleucine reduction vary by sex and strain in mice, showing a protective benefit against metabolic issues, while its increase can worsen health.
- Findings reveal that a core molecular response to dietary isoleucine exists across different sexes and strains, highlighting its potential as a dietary strategy for better metabolic health in humans.
Low-protein (LP) diets extend the lifespan of diverse species and are associated with improved metabolic health in both rodents and humans. Paradoxically, many athletes and bodybuilders consume high-protein (HP) diets and protein supplements, yet are both fit and metabolically healthy. Here, we examine this paradox using weight pulling, a validated progressive resistance exercise training regimen, in mice fed either an LP diet or an isocaloric HP diet.
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