Publications by authors named "Esther Padilha da Silveira"

Introduction: Substance abuse is a major public health problem. In recent years, ketamine, which is a parenteral anesthetic, has been consumed increasingly as an illicit drug together with alcohol, although little is known of how this association alters brain activity. The present study investigated the influence of progressive doses of ketamine, associated with alcohol, on electrophysiological activity.

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Article Synopsis
  • Smoking is a leading cause of preventable death globally, with nicotine affecting brain activity related to addiction and heart function, potentially leading to heart rhythm issues.
  • A study was conducted on Wistar rats to examine EEG and ECG patterns during nicotine exposure, withdrawal, and relapse, focusing on the impact on brainwaves and heart conduction.
  • Findings reveal that high-frequency brainwaves relate to nicotine dependence, while withdrawal emphasizes slower brain oscillations tied to cravings; nicotine can cause heart abnormalities that slightly improve with withdrawal but worsen during relapse.
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Seizures are neurological disorders triggered by an imbalance in the activity of excitatory and inhibitory neurotransmitters in the brain. When triggered chronically, this imbalance can lead to epilepsy. Critically, many of the affected individuals are refractory to treatment.

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