Publications by authors named "Esther Ngo Lemba Tom"
Ethnopharmacological Relevance: Fagara tessmannii is a shrub of the African rainforests in South-West, Centre, South and East provinces in Cameroon. It is used in traditional medicine for the treatment of tumors, swellings, inflammation, gonorrhoea, schistosomiasis, antifungal, heart diseases and as anti-hypertensive.
Aim Of The Study: We investigated the potential effects of F.
Background: Chlorogenic acid (CGA), the main polyphenol contained in coffee, is a major contributor to dietary polyphenol intake. Few studies reported its anti-hypertensive properties but the mechanisms are still indefinite.
Purpose: The present study assessed the direct effect of CGA in endothelium denuded or intact aortic rings from male Wistar rats and the mechanisms involved.
Ethnopharmacological Relevance: The leaves of Kalanchoe pinnata (Crassulaceae) are used in Cameroon folk medicine to manage many diseases such as cardiovascular dysfunctions. In this work, we aimed to evaluate the activities of aqueous leaf extract of Kalanchoe pinnata on the blood pressure of normotensive rat (NTR) and salt hypertensive rats (SHR), as well as its antioxidant properties.
Materials And Methods: Hypertension was induced in rats by oral administration of 18% NaCl for 4 weeks.
Ethnopharmacological Relevance: The stem bark of Terminalia superba (TS) is widely used as a decoction by Cameroonian folk medicine for the treatment of hypertension. The aim of the present study was to evaluate the effect of a chronic treatment with a TS extract on spontaneously hypertensive rats (SHR) with respect to efficacy, biochemical mechanisms and safety.
Materials And Methods: Eleven-week-old SHR and normotensive Wistar Kyoto rats (WKY) were daily treated by gavage with a methylene chloride extract of stem bark of Terminalia superba (TMSE, 150mg/kg) or with the vehicle for 5 weeks.
Ethnopharmacological Relevance: Jateorhiza macrantha is a medicinal plant used in popular medicine to treat several diseases, including cardiovascular disorders. To date, there is no documented report available on the toxicological profile of this medicinal plant.
The Aim Of The Study: The present study was carried out to investigate the mineral content and the safety of the oral administration of the leaf aqueous extract of Jateorhiza macrantha in mice.
Aim Of The Study: The stem bark of Terminalia superba (Combretaceae) (TS) is used in traditional Cameroonian medicine as antihypertensive remedy. The aim of this study was to investigate the hypotensive and the antihypertensive effects of the aqueous extract of the stem bark of Terminalia superba.
Materials And Methods: Hypertension was obtained in rats by oral administration of 10% D-glucose for 3 weeks.
Aim Of The Study: The stem bark of Terminalia superba (Combretaceae) (TS) is used in traditional Cameroonian medicine as antihypertensive remedy. In the present study, we investigated the vasorelaxant properties of different extracts of TS and their underlying mechanisms.
Materials And Methods: Activities of aqueous (AQU), methanolic (MET), methylene chloride (MC), and methylene chloride-methanol (MCM) extracts of TS were evaluated on isolated rat aortic rings precontracted with phenylephrine (PE) or high KCl.