Publications by authors named "Esther M Gonzalez-Gil"
Background: An increasing number of studies in recent years investigate various dietary and lifestyle patterns and associated breast cancer (BC) risk.
Objectives: This study aimed to comprehensively synthesize and grade the evidence on dietary and lifestyle patterns and BC risk.
Methods: Databases were systematically searched up to 31 March, 2022, for evidence from randomised controlled trials and prospective cohort studies on adherence to a dietary pattern alone or in combination with lifestyle behaviors and incidence of or mortality from primary BC in adult females.
Article Synopsis
- The study aimed to compare traditional and novel body shape indexes (like ABSI and HI) regarding their associations with inflammation markers, particularly C-reactive protein (CRP), using data from the EPIC and UK Biobank cohorts.
- Participants included nearly 444,000 individuals, with the analysis involving various body shape phenotypes derived from measurements such as height and weight.
- Results indicated that traditional measures like BMI and waist circumference were positively linked to CRP levels, while some body phenotypes showed varying associations by sex, highlighting the complexity of body shape and inflammation relationships.
This study aims to investigate the influence of psychosomatic and emotional status on food portion sizes (PSs) consumption from high energy-dense food groups in European children and adolescents. We hypothesized that psychosomatic and emotional status would have a significant association with the PS selection of energy-dense food. The study included 7355 children aged between 2 and 9.
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- Community- and school-based lifestyle interventions are effective in preventing type 2 diabetes but many participants drop out of follow-ups, prompting an investigation into what influences ongoing participation in a European study.
- The study analyzed the impact of socioeconomic, sociodemographic, and clinical factors on 2,702 participants from six different countries, identifying significant differences related to gender, education, employment, BMI, and blood pressure.
- Findings indicated that higher education and employment levels were linked to lower drop-out rates, particularly in high-income countries, while female participants in low-to-middle-income countries showed better retention; overall, demographics and BMI were crucial for understanding participant engagement in these programs.
The role of diet in colorectal cancer prognosis is not well understood and specific lifestyle recommendations are lacking. We searched for randomised controlled trials (RCTs) and longitudinal observational studies on post-diagnosis dietary factors, supplement use and colorectal cancer survival outcomes in PubMed and Embase from inception until 28th February 2022. Random-effects dose-response meta-analyses were conducted when at least three studies had sufficient information.
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- A systematic review was conducted on factors like body weight, physical activity, and diet, to evaluate their impact on colorectal cancer prognosis, analyzing 167 publications, mostly observational studies.
- The evidence indicated a complex, reverse J-shaped relationship between body mass index and cancer prognosis, but overall evidence quality was conservative due to potential biases.
- Limited-suggestive findings were noted for recreational physical activity and healthy dietary patterns in reducing mortality risks, highlighting the need for more robust studies to develop effective lifestyle recommendations for colorectal cancer patients.
Background: The databases of children's anthropometric parameters are often outdated, rarely representative and are not always available at an international level.
Objectives: To present children's anthropometric parameters in six European countries that contributed to the Feel4Diabetes project and find country-specific differences.
Design/setting: The Feel4Diabetes study was performed between 2016 and 2018, targeting children in Belgium, Bulgaria, Finland, Greece, Hungary and Spain.
Background: The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality.
Methods: A total of 13,270 incident breast cancer cases were identified from an initial sample of 318,686 women in 9 countries from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Article Synopsis
- A study was conducted to explore how pre-diagnostic dietary patterns linked to inflammation, insulin, and estrogen affect survival rates in breast cancer (BC) patients.
- Researchers used dietary data from a large European study and applied statistical models to analyze the relationships between various diets and overall mortality as well as BC-specific mortality.
- The findings indicated that following a diabetes risk reduction diet (DRRD) was linked to lower overall mortality, while pro-inflammatory diets were associated with a slight increase in mortality; however, no significant link was found with estrogen-related diets or BC-specific mortality.
Background: The frequency of family meals has been suggested as a protective factor against obesity among children.
Objective: This study aimed to investigate the cross-sectional and longitudinal associations between family meals frequency and children's overweight/obesity in families at high risk of type 2 diabetes (T2D) across six European countries.
Methods: 989 parent-child dyads (52% girls and 72% mothers) were included.
Objectives: The prevention of children being overweight/obese is of utmost importance. Parental characteristics play a pivotal role in shaping offspring weight status. This study aimed to examine associations between parental obesity and children's overweight/obesity status, and whether other parental type 2 diabetes (T2D) risk factors can predict children's obesity status.
View Article and Find Full Text PDFObjectives: This study aimed to investigate the associations between portion sizes (PSs) from different food groups and energy, as well as nutrient intakes in European adolescents.
Methods: A sample of 1631 adolescents (54.2 % girls) were included from the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional (HELENA) study.
Unlabelled: Puberty has been described as a life stage of considerable metabolic risk specially for those with obesity. The low-grade systemic inflammatory status associated with obesity could be one of the connections with metabolic syndrome (MetS). Thus, we aimed to assess the relationship between inflammatory and cardiovascular biomarkers and the development of MetS during puberty.
View Article and Find Full Text PDFObjective: The aim of the present study was to investigate the association of diet quality with fasting glycemia, insulinemia, and insulin resistance in a cross-sectional sample of adults from families at high risk for type 2 diabetes mellitus (T2DM) from six European countries, taking into account their socioeconomic status (SES).
Methods: Baseline data from non-diabetic adults from the Feel4 Diabetes study were used and diet was assessed by the Healthy Diet Score (HDS). Insulin resistance (IR) was determined by homeostasis model assessment of IR (HOMA-IR).
Parental food consumption and diet quality and its association with children's food consumption in families at high risk of type 2 diabetes: the Feel4Diabetes-study.
Public Health Nutr
October 2022
Objective: To examine the parental food consumption and diet quality and its associations with children's consumption in families at high risk for developing type 2 diabetes mellitus across Europe. Also, to compare food frequency consumption among parents and children from high-risk families to the European Dietary guidelines/recommendations.
Design: Cross-sectional study using Feel4diabetes FFQ.
Objectives: Socioeconomic inequalities create substantial burdens influencing children's health status and diet quality. The aim of this study was to investigate the association between cumulative socioeconomic vulnerabilities and differences in the food intake of children.
Methods: This was a cross-sectional analysis of baseline data from 12 041 European parent-child dyads (children were 5-12 y of age with 49% boys) enrolled in the Feel4 Diabetes study.
Prepubertal Children With Metabolically Healthy Obesity or Overweight Are More Active Than Their Metabolically Unhealthy Peers Irrespective of Weight Status: GENOBOX Study.
Front Nutr
April 2022
Background And Aim: The association of a metabolically healthy status with the practice of physical activity (PA) remains unclear. Sedentarism and low PA have been linked to increased cardiometabolic risk. The aim of this study was to evaluate the PA levels in metabolically healthy (MH) or unhealthy (MU) prepubertal children with or without overweight/obesity.
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- Family meals, defined as meals shared with family members or at least one parent present, are linked to healthier eating habits for both parents and children, especially in families at high risk for type 2 diabetes in Europe.
- The study found that more frequent family meals correlate with better food consumption and diet quality among parents (β = 0.84) and healthier eating patterns in children, with significant associations for both boys and girls.
- Parental diet quality partially mediates the relationship between family meal frequency and children's food consumption, particularly impacting specific food items like milk products and salty snacks, especially during family breakfasts for girls.
Unlabelled: Parental health is associated with children's health and lifestyles. Thus, the aim of the present study was to assess lifestyle behaviours of children of parents with insulin resistance (IR) and at risk of type 2 diabetes. 2117 European families from the Feel4Diabetes-study were identified as being at risk for diabetes with the FINDRISC questionnaire and included in the present study.
View Article and Find Full Text PDFObesity and cardiometabolic risk have been associated with vitamin D levels even in children. The objective of the present study was to evaluate the association between insulin resistance (IR), cardiometabolic risk factors, and vitamin D in children from prepubertal to pubertal stages. A total of 76 children from the PUBMEP study, aged 4-12 years at baseline, were included.
View Article and Find Full Text PDFBackground: Physical activity (PA) has acquired a significant relevance due to the health benefits associated with its practice. Accelerometers are an effective tool to assess PA; however, the diversity of cut-off points used to define different PA intensities through accelerometry could interfere in the interpretation of the findings among studies.
Objectives: The present study aimed to examine the sedentary behavior (SB) and physical activity (PA) levels in children using six selected accelerometry protocols based on diverse cut-off points.
The Feel4Diabetes-study implemented a school- and community-based intervention to promote healthy lifestyle and prevent type 2 diabetes mellitus (T2DM) in six European countries. The intervention included a special focus on families at increased T2DM risk. The current study evaluates the intervention's cost-effectiveness.
View Article and Find Full Text PDFBackground: This study investigated the effect of the Feel4Diabetes-intervention, a 2-year multilevel intervention, on energy balance-related behaviors among European families at risk for developing type 2 diabetes. Intervention effects on self-reported physical activity, sedentary behavior and eating behaviors were investigated across and within the participating countries: Belgium, Finland, Greece, Spain, Hungary and Bulgaria.
Methods: Families were recruited through schools, located in low socio-economic status areas.
Background: Metabolic risk and inflammatory state have an early life onset and are associated with future diseases.
Objectives: To assess the association between metabolic syndrome (MetS) and metabolic health with high-sensitive C-reactive protein (hsCRP), cross-sectionally and longitudinally, in children.
Methods: 2913 European children (2-10 years) from eight countries from the IDEFICS study were investigated.
Background: Elevated cardiometabolic risk (CMR) is an important factor for cardiovascular diseases later in life while physical fitness seems to decrease CMR.
Objective: Thus, the aim of the present study is to assess the association between muscular fitness (MF) and cardiorespiratory fitness (CRF) on CMR in European children, both cross-sectional and longitudinally.
Methods: A total of 289 children (49.