Publications by authors named "Esther Klonowski"
(.) ITS genotype VIII, also known as , is a new species of the / complex and its first records, albeit under a different species name, are from the Indian subcontinent, Middle Eastern Asia, and West Asia genotype VIII (. ) has spread globally and has now been documented in over 30 countries.
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- * For conditions like pityriasis versicolor and severe dermatophytoses, treatments may involve oral medications, although many oral antifungals are off-label for kids in Germany; combining oral and topical therapies is recommended.
- * Terbinafine resistance is common in some dermatophyte infections, prompting the need for species identification and resistance testing; itraconazole is preferred for resistant cases, with alternative therapies like laser and photodynamic therapy also available.
Article Synopsis
- Traditional methods for identifying dermatophytes, like culture and fluorescence microscopy, are now being enhanced by molecular techniques, specifically uniplex-PCR-EIA for nail samples.
- A study with 108 patients revealed that conventional identification methods combined with molecular analysis yielded reliable results, efficiently detecting common pathogens Trichophyton rubrum and Trichophyton interdigitale.
- The use of PCR demonstrated high specificity and sensitivity, even identifying dermatophytes in samples that didn’t show cultural growth, making it a valuable tool for accurate diagnosis.
Onychomycosis is a common infectious nail disease occurring worldwide. The mycological diagnosis of onychomycosis is primarily used for differential diagnostic differentiation from other, mostly inflammatory nail diseases, such as nail psoriasis or onychodystrophies of other causes. Conventional laboratory diagnostics when onychomycosis is suspected is based on microscopic detection of fungi in the nail material using fluorescence-optical potassium hydroxide preparations and culture of the pathogen.
View Article and Find Full Text PDF[Clinical picture, causative agents and diagnostics of dermatomycoses].
Dermatologie (Heidelb)
December 2022
Article Synopsis
- - Dermatomycoses, caused mainly by dermatophytes, affect various body areas including skin, hair, fingernails, and toenails, impacting populations like the elderly, infants, and immunocompromised individuals more frequently.
- - Candida albicans is a key player in yeast infections, targeting intertriginous areas and leading to oral mucosal infections, especially in patients with HIV/AIDS.
- - The diagnosis of dermatophyte infections involves microscopic examination and culture, but molecular methods like PCR are increasingly considered the gold standard due to their accuracy in detecting fungal species.
Three boys from the same city, treated by the same dermatologist, developed tinea capitis. Two of them, 4 and 8 years old, underwent mycological diagnostic workup. However, no pathogens familiar in this country, such as Microsporum (M.
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