Publications by authors named "Esther Kisaakye"
Introduction: isoniazid preventive therapy (IPT) is highly effective at preventing tuberculosis among Persons Living with HIV (PLHIV). However, IPT completion rates in Uganda have not been studied. We examined completion rates for the 6-month course of IPT and factors associated with non-completion among PLHIV in northeastern Uganda.
View Article and Find Full Text PDFBackground: Substance use disorders (SUD) pose a significant public health problem in Uganda. Studies indicate that integrating mental health services into Primary Health Care can play a crucial role in alleviating the impact of SUD. However, despite ongoing efforts to integrate these services in Uganda, there is a lack of evidence regarding the preparedness of health facilities to effectively screen and manage SUD.
View Article and Find Full Text PDFTrends and spatial distribution of neonatal sepsis, Uganda, 2016-2020.
BMC Pregnancy Childbirth
November 2023
Article Synopsis
- Neonatal sepsis is a significant health issue in Uganda, being the third leading cause of neonatal deaths, with early-onset sepsis (EOS) being more prevalent than late-onset sepsis (LOS) from 2016 to 2020.
- A study analyzing data from the District Health Information System revealed an overall incidence of 17.4 cases of sepsis per 1,000 live births, with EOS cases rising while LOS cases decreased.
- The findings indicate a critical need for improved prevention strategies and healthcare quality for pregnant women, especially given the varying trends and distributions of sepsis across different regions and healthcare facilities.
Background: Kampala city slums, with one million dwellers living in poor sanitary conditions, frequently experience cholera outbreaks. On 6 January 2019, Rubaga Division notified the Uganda Ministry of Health of a suspected cholera outbreak in Sembule village. We investigated to identify the source and mode of transmission, and recommended evidence-based interventions.
View Article and Find Full Text PDFBackground: Following a finding of alcohol use among children aged 5-8 years old in Mbale, Uganda, this project investigates the magnitude of alcohol and substance use among children ged 6-13 years old and related household, community, school, health system and clinical factors.
Methods: The project includes four larger work packages (WPs). WP1 comprises management, WP2 and 3 include the scientific components and WP4 includes integration of results, dissemination, policy and implementation advice.
Article Synopsis
- Crimean-Congo haemorrhagic fever (CCHF) is a viral disease transmitted by ticks, causing severe hemorrhagic symptoms, with multiple outbreaks reported in Uganda, primarily in the 'cattle corridor'.
- A study conducted from July 2018 to January 2019 identified 14 confirmed cases, all with fever and a high prevalence of unexplained bleeding, resulting in a significant case-fatality rate of 36%.
- Risk factors included close contact with livestock, living near grazing fields, and a high incidence of tick attachment, highlighting the need for targeted interventions to prevent future outbreaks.
On April 20, 2018, the Kween District Health Office in Kween District, Uganda reported 7 suspected cases of human anthrax. A team from the Uganda Ministry of Health and partners investigated and identified 49 cases, 3 confirmed and 46 suspected; no deaths were reported. Multiple exposures from handling the carcass of a cow that had died suddenly were significantly associated with cutaneous anthrax, whereas eating meat from that cow was associated with gastrointestinal anthrax.
View Article and Find Full Text PDFArticle Synopsis
- - The Uganda Ministry of Health announced a cholera outbreak in the Kyangwali Refugee Settlement on February 23, 2018, with over 60 individuals affected, leading to an investigative study to assess the outbreak's extent and transmission methods.
- - Investigators defined cholera cases based on symptoms and conducted a case-control study, finding a case-fatality rate of 2.1% with the highest impact on individuals from the Democratic Republic of Congo.
- - The outbreak lasted four months and was linked to contaminated stream water resulting from open defecation, with an overall attack rate of 3.2 per 1000 people in Hoima District.
Introduction: the principal burden of human papillomavirus (HPV) infections is cervical cancer. Cervical cancer ranks as the fourth most common malignancy in women affecting 500,000 women each year with an estimated 266,000 deaths. Uganda has one of the highest cervical cancer incidence rates globally with an age-standardised incidence rate per 100,000 of 47.
View Article and Find Full Text PDF