Publications by authors named "Esther Gonzalez Villar"

Objective: This study investigated the effectiveness and tolerability of brivaracetam (BRV) monotherapy in a large series of patients with epilepsy.

Method: This was a multicenter, retrospective, observational, non-interventional study in 24 hospitals across Spain. Patients aged ≥18 years who started on BRV monotherapy, either as first-line or following conversion, at least 1 year before database closure were included.

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Article Synopsis
  • Researchers analyzed ischaemic stroke (IS) cases that occurred within eight days of COVID-19 onset to determine if they have a unique genetic background compared to other stroke types.
  • Using a method called SUPERGNOVA, they identified specific genomic regions related to large artery atherosclerosis (LAA) and cardioembolic stroke (CES) from a cohort of 73 IS-COV patients and 701 control subjects.
  • The study found four genetic loci associated with CES and significant polygenic risk scores for LAA, suggesting IS-COV patients may share genetic traits with these stroke subtypes; more research is needed to see if these traits are specific to viral infection or common in the general population.
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Background: We aimed to assess the risk of developing new-onset seizures or seizure decompensations in people with epilepsy (PWE) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

Methods: A retrospective observational study in a tertiary hospital was conducted. Clinical records of all patients attended because of seizures or epilepsy at outpatient clinics, emergency department, or admitted to our hospital from January to December 2021 were reviewed, including patients older than 16 years who received some dose of coronavirus disease 2019 (COVID-19) vaccines.

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Background: The aim of this study was to have a better understanding of the influence of the coronavirus disease 2019 (COVID-19) pandemic in people with epilepsy (PWE) and to assess whether there have been changes in seizure control during the current COVID-19 outbreak, exploring the possible causes thereof.

Methods: This is an observational, retrospective study based on prospective data collection of 100 successive patients who attended an epilepsy outpatient clinic either face-to-face or telephonically during the months of the COVID-19 outbreak and national state of emergency.

Results: One hundred patients were included, 52% women, mean age 42.

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