Publications by authors named "Esther Cantero-Cano"
Article Synopsis
- The study investigates how polyamine levels during pregnancy are linked to maternal allergies and immune responses in newborns.
- Spermidine and spermine were found to be the main polyamines in both mothers and their newborns, with lower spermine levels associated with maternal allergic conditions, particularly allergic conjunctivitis.
- Higher levels of polyamines in cord blood correlated with an increased number of lymphocytes and reduced production of inflammatory and Th2-related cytokines, suggesting a potential protective effect against allergies in infants.
Background: Outdoor air pollution may disturb immune system development. We investigated whether gestational exposure to traffic-related air pollutants (TRAP) is associated with unstimulated cytokine profiles in newborns.
Methods: Data come from 235 newborns of the NELA cohort.
The prevalence of asthma is considerably high among women of childbearing age. Most asthmatic women also often have other atopic disorders. Therefore, the differentiation between patients with atopic diseases without asthma and asthmatics with coexisting diseases is essential to avoid underdiagnosis of asthma and to design strategies to reduce symptom severity and improve quality of life of patients.
View Article and Find Full Text PDFBackground: Hazards of traffic-related air pollution (TRAP) on the developing immune system are poorly understood. We sought to investigate the effects of prenatal exposure to TRAP on cord blood immune cell distributions; and to identify gestational windows of susceptibility.
Methods: In-depth immunophenotyping of cord blood leukocyte and lymphocyte subsets was performed by flow cytometry in 190 newborns embedded in the Nutrition in Early Life and Asthma (NELA) birth cohort (2015-2018).