Publications by authors named "Esther C Dos Reis"
This paper presents a methodology for automatically extracting insights from PubMed articles using a Natural Language Processing (NLP) framework. Our approach, leveraging advanced NLP techniques and Named Entity Recognition (NER), is crucial for advancing pharmacogenomics and other scientific fields that benefit from streamlined access to literature through automated services like RESTful APIs.Building a new NLP model presents several challenges.
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- The study aimed to analyze the pharmacogenetic profiles of Brazilian psychiatric patients based on their ethnic backgrounds.
- It utilized the GnTech database and assessed data from 359 patients, focusing on 26 key pharmacogenes that influence responses to psychotropic drugs.
- The findings indicated significant differences in pharmacogene variant frequencies across different ethnic groups, highlighting the importance of personalized medicine in drug treatment decisions, particularly in Brazil's diverse population.
Background: The correct understanding of the epidemiological dynamics of COVID-19, caused by the SARS-CoV-2, is essential for formulating public policies of disease containment.
Methods: In this study, we constructed a picture of the epidemiological dynamics of COVID-19 in a Brazilian population of almost 17000 patients in 15 months. We specifically studied the fluctuations of COVID-19 cases and deaths due to COVID-19 over time according to host gender, age, viral load, and genetic variants.