The challenge of preoperative identification of uterine myomas: Is ultrasound trustworthy? A prospective cohort study.

Purpose: To correlate preoperative ultrasound examination with intraoperative and anatomo-pathological findings, including estimation of number, localization and size of uterine myomas, uterine diameters and volume.

Methods: A prospective study on 126 women undergoing surgery for uterine myomatosis at Campus Bio-medico between May 2013 and April 2014. The patients were divided into two groups: one submitted to hysterectomy and the other submitted to open myomectomy.

Influence of pneumoperitoneum pressure on surgical field during robotic and laparoscopic surgery: a comparative study.

Purpose: Studies on the influence of CO₂ pneumoperitoneum on the abdominal cavity during robotic procedures are lacking. This is the first study to evaluate surgical field modifications related to CO₂ pressure, during laparoscopic and robotic surgery.

Methods: Consecutive patients scheduled for laparoscopic or robotic hysterectomy were enrolled in the study.

Surgical treatment of rectovaginal endometriosis with extensive vaginal infiltration: results of a systematic three-step vagino-laparoscopic approach.

Objective: Recto-vaginal endometriosis remains a surgical challenge. We propose a systematic surgical approach combining vaginal and laparoscopic steps for patients affected by deep endometriosis infiltrating the vaginal wall.

Study Design: This is a prospective observational study, performed at Campus Bio-Medico of Rome, University Teaching Hospital.

A comparison of three different entry techniques in gynecological laparoscopic surgery: a randomized prospective trial.

Objective: Laparoscopic entry techniques vary and still remain debated. We conducted a randomized control trial to compare three entry techniques.

Study Design: Women aged 18-70 years, nominated for laparoscopic surgery at University of Rome Campus Bio-Medico, were randomized into three different groups: Veress needle (VER), Direct trocar insertion (DIR) and Open technique (OP).

REM (risk of endometrial malignancy): a proposal for a new scoring system to evaluate risk of endometrial malignancy.

Purpose: It is often difficult to distinguish a benign endometrial disease from a malignancy and tools to help the physician are needed to triage patients into high and low risk of endometrial cancer. The purpose of this study was to obtain a predictive model to assess the risk of endometrial malignancy (REM) in women with ultrasound endometrial abnormalities.

Experimental Design: Women, between ages 45 to 80 years, diagnosed through ultrasound with endometrial abnormalities and scheduled to have surgery were enrolled on a prospective study at the Department of Gynaecologic Oncology of Campus Bio-Medico, University of Rome.

Use of music to reduce anxiety during office hysteroscopy: prospective randomized trial.

Study Objective: To investigate the effects of music on anxiety and perception of pain during office hysteroscopy.

Design: Prospective randomized trial (Canadian Task Force classification I).

Setting: Major university medical center.

Quality of life in patients with endometrial cancer treated with or without systematic lymphadenectomy.

Objective: To compare the quality of life (QoL) of women affected by endometrial cancer treated with surgery with or without systematic lymphadenectomy.

Study Design: Consecutive patients affected by stages I and II endometrial cancer and treated with surgery between 2008 and 2011 were selected. Eligible subjects were divided into two groups: Group A consisted of 36 patients who had hysterectomy plus bilateral salpingo-oophorectomy without lymphadenectomy; Group B consisted of 40 patients who had hysterectomy plus salpingo-oophorectomy plus pelvic and aortic lymphadenectomy.

Prenatal diagnosis of a fetus with a ring chromosome 20 characterized by array-CGH.

Objective: a fetus with a ring chromosome 20 is presented.

Methods: at 16 weeks' gestation, ultrasound examination evidenced no apparent structural malformation. Amniocentesis was performed for maternal anxiety.

Thyroid physiology and common diseases in pregnancy: review of literature.

Thyroid diseases are common during pregnancy and an adequate treatment is important to prevent adverse maternal and fetal outcomes. Subclinical diseases are very frequent but not easily recognized without specific screening programs. In this article we try to summarize the knowledge on the physiologic change of the thyroid and pathological function during pregnancy; we also try to describe the best way of diagnosis and treatment of thyroid dysfunction.

Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence.

Amniotic band sequence (ABS) is the term applied to a wide range of congenital anomalies, most typically limb and digital amputations and constriction rings, that occur in association with fibrous bands (1). These alterations may be associated or not with cutaneous and visceral abnormalities.This work, which is a literature review, examines several studies that relate to cases of amniotic band syndrome (SBA).

Can the preoperative HE4 level predict optimal cytoreduction in patients with advanced ovarian carcinoma?

Objective: Optimal surgical outcome has been proved to be one of the most powerful survival determinants in the management of ovarian cancer patients. Actually, for ovarian cancer patients there is no general consensus on the preoperatively establishment of cytoreducibility.

Methods: Between January 2011 and June 2012 patients affected by suspicious advanced ovarian cancer, referred to the Department of Gynecology of Campus Biomedico of Rome were enrolled in the study.

The role of novel biomarker HE4 in endometrial cancer: a case control prospective study.

The aim of the study was to explore the clinical value of serum human epididymis secretory protein E4 (HE4) and CA125 in endometrial carcinoma. From January 2010 to April 2012, serum specimens were collected from consecutive cases of endometrial carcinoma and from cases of uterus benign disease (control group). The CA125 normal value is considered less than 35 U/mL.

Intraoperative contact ultrasonography during open myomectomy for uterine fibroids.

Objective: To evaluate the benefit of intraoperative ultrasound applied directly to the uterine serosa during surgery for uterine fibroids.

Design: Prospective study.

Setting: University hospital, tertiary care.

A gastrointestinal stromal tumor presenting as a pelvic mass: A case report.

Gastrointestinal stromal tumors (GISTs) represent 0.1-1% of gastrointestinal malignancies. They are commonly asymptomatic and found incidentally during laparoscopy, surgical procedures or radiological studies.

Update on lymphadenectomy in early and advanced ovarian cancer.

Purpose Of Review: Pelvic and para-aortic lymphnode sampling is an integral part of the staging system of ovarian cancer. The issue concerning lymphadenectomy in the management of the disease is still debated, however. The purpose of this paper is to review the role of systematic lymphadenectomy in patients affected by early and advanced-stage ovarian cancer.