The association of quantitative EEG and MRI in Creutzfeldt-Jakob Disease.

Introduction: Previous studies showed concordance between the typical Periodic Sharp Wave Complex (PSWC) activity in EEG of Creutzfeldt-Jakob Disease (CJD) patients and the MRI findings, while the concordance with slow activity in EEG is less established. The aim of this study was to better characterize the association between MRI findings and EEG changes using quantitative EEG (qEEG) analysis.

Methods: The demographics, clinical features, and the MRI findings of 12 familial E200K patients with CJD were gathered.