Publications by authors named "Ester Jimenez"
Article Synopsis
- * A study compared DNA methylation profiles between excellent responders to Li and non-responders, identifying 130 differentially methylated positions and linking them to several genes associated with Li response, particularly in the GSK3β pathway.
- * Despite finding a specific methylation pattern that may predict Li response, no significant differences in age acceleration were observed between responders and non-responders, suggesting more research is needed to explore the underlying mechanisms.
Pharmacological treatment for psychiatric disorders has shown to only be effective in about one-third of patients, as it is associated with frequent treatment failure, often because of side effects, and a long process of trial-and-error pharmacotherapy until an effective and tolerable treatment is found. This notion emphasizes the urgency for a personalized medicine approach in psychiatry. This prospective patient- and rater-blinded, randomized, controlled study will investigate the effect of dose-adjustment of antidepressants and or antipsychotics and according to the latest state-of-the-art international dosing recommendations for and metabolizer status in patients with mood, anxiety, and psychotic disorders.
View Article and Find Full Text PDFObjective: To evaluate in vitro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.
Methods: A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use. The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi (Aspergillus fumigatus), yeast (Candida albicans), gram-negative (Acinetobacter baumannii and Pseudomonas aeruginosa) and gram-positive bacteria (Staphylococcus aureus).