Publications by authors named "Estefania Enebral-Romero"

In this work, we present an electrochemical sensor for fast, low-cost, and easy detection of the SARS-CoV-2 spike protein in infected patients. The sensor is based on a selected combination of nanomaterials with a specific purpose. A bioconjugate formed by Few-layer bismuthene nanosheets (FLB) and tetrahedral DNA nanostructures (TDNs) is immobilized on Carbon Screen-Printed Electrodes (CSPE).

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In this work we present the development of an electrochemiluminescence aptasensor based on electrografting molybdenum disulphide nanosheets functionalized with diazonium salt (MoS-N) upon screen-printed electrodes of graphene (SPEs GPH) for viral proteins detection. In brief, this aptasensor consists of SPEs GPH electrografted with MoS-N and modified with a thiolated aptamer, which can specifically recognize the target protein analyte. In this case, we have used SARS-CoV-2 spike protein as model protein.

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Article Synopsis
  • - A new portable DNA biosensor has been created that detects multiple bacteria at once, featuring a low-cost and efficient design.
  • - It uses a potentiostat to control the electrochemical process on a specialized platform and monitors current reactions with thionine-functionalized carbon nanodots as indicators.
  • - The biosensor is user-friendly, compatible with devices like phones and tablets, and shows better performance than traditional lab-based systems in detecting specific bacterial DNA sequences.
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This work focuses on the combination of molybdenum disulfide (MoS) and à la carte functionalized carbon nanodots (CNDs) for the development of DNA biosensors for selective and sensitive detection of pathogens. MoS flakes prepared through liquid-phase exfoliation, serves as platform for thiolated DNA probe immobilization, while thionine functionalized carbon nanodots (Thi-CNDs) are used as electrochemical indicator of the hybridization event. Spectroscopic and electrochemical studies confirmed the interaction of Thi-CNDs with DNA.

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