Publications by authors named "Esteban A Molina"
Article Synopsis
- Infection can delay burn wound healing, increasing complications and scarring, necessitating an effective antimicrobial that spares skin cells crucial for recovery.
- The study evaluated a handheld device, the Aceso Plasma Generator, which produces Aceso Cold Plasma (ACP), demonstrating its effectiveness in killing bacteria without hindering wound healing in tested animals.
- ACP appears to be a promising treatment for reducing infection risk in acute burn injuries and may also benefit wounds prone to delayed healing and scarring, offering a new method for efficient wound management.
Objectives: Dyschromia is an understudied aspect of hypertrophic scar (HTS). The use of topical tacrolimus has successfully shown repigmentation in vitiligo patients through promotion of melanogenesis and melanocyte proliferation. It was hypothesized that HTSs treated with topical tacrolimus would have increased repigmentation compared to controls.
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- Hypertrophic scar (HTS) formation is a major issue for burn injury patients, with dermal microvascular endothelial cells (DMVECs) playing a key but under-researched role in this process.
- The study discovered that DMVECs in HTS exhibited significant differences in gene expression and functionality compared to those from normal skin, including altered permeability and a specific profile of 31 differentially expressed genes.
- Results indicated that HTS DMVECs have a unique response to injury, being less permeable and displaying mixed factors that can affect scar formation, suggesting their important role in understanding and treating HTS development.
Objective: It has not been well-elucidated whether there are advantages to preserving bone flaps in abdominal subcutaneous (SQ) tissue after decompressive hemicraniectomy (DHC), compared to discarding bone flaps. The authors aimed to compare perioperative outcomes and costs for patients undergoing autologous cranioplasty (AC) after DHC with the bone flap preserved in abdominal SQ tissue, and for patients undergoing synthetic cranioplasty (SC).
Methods: A retrospective review was performed of all patients undergoing DHC procedures between January 2017 and July 2021 at two tertiary care institutions.