Diagnosis and treatment of nodules remain challenging issues. The aim of this article is to report the technique of real-time navigation using holographic reconstruction technology combined with a robot assisted thoracic surgery (RATS) platform for lung resection in patients with . The pre-surgery 3D planning was based on the chest CT scan.
View Article and Find Full Text PDFUnlabelled: This study aimed to assess the antileishmanial activity of biomolecules obtained from L. leaves and twigs recovered from eight Tunisian cultivars. The extraction was first carried out with 80% methanol, and then the obtained extract was fractionated using three solvents of increasing polarity: cyclohexane (CHX), dichloromethane (DCM) and ethyl acetate (EtOAc).
View Article and Find Full Text PDFAim: The present study aimed to investigate a novel antifungal compound produced by Streptomyces blastmyceticus S108 strain. Its effectiveness against clinical isolates of Candida species and its synergistic effect with conventional antifungal drugs were assessed, and its molecular mechanism of action was further studied against Candida albicans.
Methods And Results: A newly isolated strain from Tunisian soil, S.
Combination therapy at appropriately suitable doses presents a promising alternative to monotherapeutic drugs. In this study, and essential oils and their major compounds have exhibited substantial leishmaniacidal potential against both promastigote and amastigote forms of . However, they displayed high cytotoxicity against Raw264.
View Article and Find Full Text PDFNanoencapsulation is widely considered as a highly effective strategy to enhance essential oils' (EO) stability by protecting them from oxidative deterioration and evaporation. The present study aims to optimize and characterize an efficient technique for encapsulating essential oil into chitosan nanoparticles using response surface methodology (RSM). Moreover, the optimized EO nanoparticle was investigated for its antibacterial (against Gram-positive and Gram-negative bacteria), antifungal (against ), and antiparasitic activity (against parasites).
View Article and Find Full Text PDFPurpose: Leishmaniasis is a parasitic disease found in tropical areas, and it affects up to 12 million individuals globally. Chemotherapies now available include drawbacks such as toxicity, high cost, and parasite resistance. This work aimed to evaluate the antileishmanial properties of essential oils (EOs) extracted from aerial parts of Cupressus sempervirens (C.
View Article and Find Full Text PDFFood Sci Technol Int
October 2023
Current study aims to evaluate the effect of essential oil on the conservation of chicken fillets. Following a screening, was selected for its antimicrobial ( ATCC 29212, MIC < 0.031 mg/mL) and antioxidant (IC = 1000 µg/mL) potentials with no cytotoxicity effect towards murine macrophage cells.
View Article and Find Full Text PDFPrimary retroperitoneal cavernous hemangioma is an extremely rare disease in clinical practice. It is classified as a vascular tumor. Only three cases have been reported in the literature.
View Article and Find Full Text PDFSchwannoma is a type of nerve tumor of the nerve sheath. They are preferentially localized on the head, neck, and flexor surfaces of the extremities. Retroperitoneal schwannoma is extremely rare.
View Article and Find Full Text PDFThe aim of this study was to investigate antimicrobial and antioxidant activities of different fractions obtained from edible Tunisian Ziziphus Lotus leaves of Tozeur region. Different organic extracts were tested: cyclohexane, dichloromethane, ethyl acetate, n-butanol and water. Bio-guided fractionation revealed that dichloromethane fraction is the most active against S.
View Article and Find Full Text PDFIntroduction And Importance: Primary adenoid cystic carcinoma (ACC) of the lung is extremely rare. This tumor can be asymptomatic or have non characteristics symptoms, and the diagnosis is often late. The treatment of choice is surgery when it's possible.
View Article and Find Full Text PDFCyclic lipopeptides produced by Bacillus species exhibit interesting therapeutic potential. However, their clinical use remains limited due to their low stability, undesirable interactions with host macromolecules, and their potential toxicity to mammalian cells. The present work aims to develop suitable lipopeptide-loaded chitosan nanoparticles with improved biological properties and reduced toxicity.
View Article and Find Full Text PDFThe use of synthetic food additive and the appearance of antibiotic resistance are at the basis of important human health problems. The substitution of synthetic compounds with new natural substances extracted from plants or microorganisms is therefore the ideal solution to this scourge. The objective of this work was to evaluate the phyto-constituents (polyphenols, flavonoids and condensed tannins), and to test the biological activities (antioxidant, antibacterial and antiviral) of the Ajuga iva (L) aerial part extracts.
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