Metabolic phenotyping reveals a potential link between elevated faecal amino acids, diet and symptom severity in individuals with severe mental illness.

The brain-gut axis is increasingly recognized as an important contributing factor in the onset and progression of severe mental illnesses such as schizophrenia spectrum disorders and bipolar disorder. This study investigates associations between levels of faecal metabolites identified using H-NMR, clinical parameters, and dietary components of forty-two individuals diagnosed in a transdiagnostic approach to have severe mental illness. Faecal levels of the amino acids; alanine, leucine, and valine showed a significant positive correlation with psychiatric symptom severity as well as with dairy intake.

Viewpoint Analysis for Maturity Classification of Sweet Peppers.

The effect of camera viewpoint and fruit orientation on the performance of a sweet pepper maturity level classification algorithm was evaluated. Image datasets of sweet peppers harvested from a commercial greenhouse were collected using two different methods, resulting in 789 RGB-Red Green Blue (images acquired in a photocell) and 417 RGB-D-Red Green Blue-Depth (images acquired by a robotic arm in the laboratory), which are published as part of this paper. Maturity level classification was performed using a random forest algorithm.

Influence of time to treatment on early infarct-related artery patency after different thrombolytic regimens. ALKK-Study Group.

Background: In an in vitro model, recombinant tissue-type plasminogen activator was significantly more effective than streptokinase in dissolving 24-hour-old human blood clots. Therefore there might be a difference in the effect of time to treatment on the efficacy of these fibrinolytics with different fibrin specificity in patients with acute myocardial infarction.

Methods And Results: The effect of the interval between symptom onset and initiation of therapy on the efficacy of 6 different thrombolytic regimens was studied in a retrospective analysis of 6 angiographic trials with similar design.

Determinants of infarct size in patients successfully treated by intracoronary thrombolysis.

In 125 patients successfully treated by intracoronary thrombolysis, data were analyzed to determine the amount of regional wall motion impairment. In 85 patients with complete occlusion of the affected vessel and successful recanalization, ventriculographic study could be performed immediately after recanalization of the vessel and repeated 3 days thereafter. Unexpectedly, no correlation could be seen between the amount of wall motion impairment and the time interval of coronary vessel occlusion.

Fungal arthritis simulating juvenile rheumatoid arthritis.

Petriellidium boydii is often isolated from maduromycosis but has recently been associated with arthritis. A previously healthy 6-year-old boy developed chronic purulent arthritis of the knee after a bicycle accident. Culture of aspirate grew no pathogens and antibiotic treatment had no effect.

Spontaneous course of ST-segment elevation in acute anterior myocardial infarction.

The spontaneous course of ST-segment elevation (sigmaST) in 24 patients with acute anterior myocardial infarction (AMI) was studied by precordial ST-segment mapping, which was recorded at 2-hour intervals during the first 48 hours after admission. Change of sigmaST between two registrations was expressed as mV/hr, and was compared with clinical and hemodynamic parameters, course of MB-CK curve, calculated infarct mass and arrhythmias. After an initial rapid increase, there was a decrease of sigmaST, which reaches a plateau-like curve approximately 12 hours after the onset of chest pain.